三江地区妊娠妇女风疹病毒感染的血清学分析  

Serology analysis of Rubella virus infection pregnant women in Sanjiang region

作　　者：马淑霞[1] 施忠凯[2] 薛艳华[1] 王春敏[1] 杨春佳[1] 李丽秋[1] 杨景云[1] 

机构地区：[1]佳木斯大学基础医学院微生物教研室,黑龙江佳木斯154007 [2]黑龙江省医院检验科,黑龙江哈尔滨150000

出　　处：《中国微生态学杂志》2006年第5期346-347,共2页Chinese Journal of Microecology

基　　金：黑龙江省卫生厅资助项目

摘　　要：目的调查2005年三江地区妊娠妇女风疹病毒感染情况。方法收集400例妊娠8～24周孕妇血清，采用酶联免疫吸附法（ELISA）检测风疹特异性IgM抗体，对IgM阳性患者进一步用PCR检测风疹病毒RNA，对该人群的风疹病毒感染率进行调查。结果检测400例孕妇风疹病毒IgM，阳性20例，阳性率为5．00％；检测IgM阳性者的风疹病毒RNA，结果阳性8例，占IgM阳性者的40．00％。结论用ELISA和PCR法进行妊娠早期风疹病毒感染的检测，对降低先天性风疹综合征患儿的出现具有重要意义。Objective To survey the Rubella virus immune status of pregnant women in Sanjiang region. Methods Collected 400 examples pregnancy 8～24 weeks pregnant women serum, ELISA was used to survey Rubella virus special IgM in pregnant woman serum. The positive serum was surveyed Rubella virus RNA by PCR again, in order to investigate Rubella virus infection positive rate in the group. Results The IgM positive pregnant women was 20 in investigated 400 pregnant women , the positive rate was 5.00% ; The RNA positive pregnant women was 8 of the IgM positive pregnant women, the positive rate was 40% in the IgM positive women. Conclusion Detecting the early pregnancy Rubella virus infection with ELISA and the PCR, so as to reduce the appearance of congenital rubella syndrome infant have a vital significance.

关 键 词：风疹病毒 IGM 妊娠妇女 

分 类 号：R511.2[医药卫生—内科学]