氩激光虹膜切除术后暂时性眼压升高机制的实验研究  

Experimental Study on the Mechanisms of Transient Increase of Intraocular Pressure after Argon Laser Iridectomy

作　　者：何剑峰 孟瑞华[1,2] 孟旭霞[1,2] 仇宜解[1,2] 

机构地区：[1]广西柳州市第一人民医院眼科 [2]青岛医学院附属医院眼科

出　　处：《中国激光医学杂志》1996年第4期205-208,共4页Chinese Journal of Laser Medicine & Surgery

摘　　要：为探索氩激光虹膜切除术后暂时性眼压升高的发生机制，观测了兔眼激光虹膜切除术后房水前列腺素Ｅ２（ＰＧＥ２）和超氧化物歧化酶活性的动态变化与眼压升高的关系及消炎痛、维生素Ｅ等药物的防治作用。结果显示：氩激光术后暂时性眼压升高与房水ＰＧＥ２浓度升高和ＳＯＤ活性下降有关，术前应用消炎痛、考的松和维生素Ｃ、维生素Ｅ对眼压升高有防治作用。To study the mechanisms of transient increase of intraocular pressure after argon laser iridectomy, 25 rabbits were divided into 5 groups. The relations between the changes of SOD, PGE 2 in aqueous and the intraocular pressure after argon laser iridectomy were investigated. The results showed that the transient increase of the intraocular pressure after argon laser iridectomy is related with either increasing of the concentration of PGE 2 and decreasing of the activity of SOD in aqueous, and it can be prevented by using indomethacin, cortisone, Vit. E or Vit. C before the argon laser iridectomy.

关 键 词：兔眼 氩激光 虹膜切除术 眼压 超氧化物歧化酶 

分 类 号：R779.63[医药卫生—眼科]