艾亚林对牙周炎患者龈沟液中IL-1的影响  

Influence of Aiyalin to IL-1 in Gingival Crevicular Fluid of Periodontitis Patients

作　　者：谭葆春[1] 杨明华[1] 钱海峰[1] 肖健平[1] 吴文蕾[1] 林楠[1] 

机构地区：[1]南京市口腔医院牙周科,江苏南京210008

出　　处：《口腔医学研究》2006年第5期498-500,共3页Journal of Oral Science Research

摘　　要：目的:研究艾亚林(盐酸米诺环素牙用缓释膜)对牙周炎患者龈沟液中IL-1和临床症状的影响。方法:选择门诊病人中、重度慢性牙周炎患者30例,分别于使用艾亚林前后检测牙周探诊深度、附着丧失、探诊出血、记录松动度、牙龈指数,龈沟液量及IL-1浓度。结果:除附着丧失和松动度外,其他指标在用药前后均有显著性差异。结论:艾亚林可明显减轻牙周炎患者的临床症状,有效抑制炎症介质IL-1的产生。Objective： To study the influence of aiyalin （ Minocycline HCL dental S. R. Pellicle） to IL - 1 in gingival erevicular fluid and to clinical symptoms of periodontal patients. Methods： We choose medium to serious periodontitis patients, then test probing depth, attachment loss, bleeding on probing, gingival index, loosen degree, quantity of gingival crevieular fluid and IL - 1 before and after using aiyalin. Results： The difference of all indices before and after using aiyalin are statistically significant except attachment loss and loosen degree. Conclusion： Aiyalin can reduce the clinical symptoms of periodontal and inhibit the production of IL - 1,

关 键 词：牙周炎 盐酸米诺环素 IL-1 

分 类 号：R781.42[医药卫生—口腔医学]