大鼠孕早期超声辐照的后期效应研究  

Effect of diagnostic ultrasound on fetus rats’morphology in early pregnancy

作　　者：霍丽蓉[1] 刘晋敏[2] 刘望彭[3] 

机构地区：[1]山西医科大学基础医学院微生物与免疫学教研室,太原030001 [2]山西医科大学公共卫生学院 [3]山西医科大学第一临床医学院B超室

出　　处：《山西医科大学学报》2006年第8期793-794,共2页Journal of Shanxi Medical University

摘　　要：目的用探头频率为5 MHzA Dornier AI5200型彩超辐照孕早期大鼠,观察其对子代的影响来评价诊断级超声的安全性。方法按辐照诊断剂量将孕鼠随机分组,对子代进行形态学观察及数据的统计分析。结果5min组大鼠在孕早期接受超声辐照后,其子代身高、体重、肾重、肝/体比及肾/体比与对照组均无显著性差异;10min组与对照组相比肾重显著下降(P<0.01),肾/体比值也显著降低(P<0.01)。结论大鼠孕早期接受一定剂量超声辐照能够对子代的发育产生一定影响,尤其体现在肾脏重量的减轻及肾/体的下降方面。Objective To assess the diagnosis safety by A Dornier AI 5200 color Doppler ultrasound radiating rats in early pregnancy. Methods The changes of fetus morphology exposed to diagnostic ultrasound were detected and analyzed. Results In 5 min group,all data of fetus rats had no difference between experimental group and control group. In 10 min group,the weight of kidney were significantly lower than in control group （ P 〈 0.01 ）. Conclusion Diagnostic ultrasound in early pregnancy can make offspring to suffer some effects, especially, effect on kidney.

关 键 词：超声诊断 孕鼠 肾/体比 

分 类 号：R445.1[医药卫生—影像医学与核医学]