大肠癌3种化疗方案的成本-效果分析  

Cost-effectiveness Analysis of Three Chemotherapy Schemes for the Treatment of Colorectal Carcinoma

作　　者：殷克[1] 宫爱民[1] 孙特[2] 

机构地区：[1]大连大学附属医院肛肠科,辽宁大连116021 [2]武警辽宁总队大连医院

出　　处：《中国肛肠病杂志》2006年第10期17-19,共3页Chinese Journal of Coloproctology

摘　　要：研究晚期大肠癌3种化疗方案的经济效果。将106例晚期大肠癌患者随机分为LF组（注射用亚叶酸钙＋注射用5-氟尿嘧啶）、HDLF组（注射用羟基喜树碱＋顺铂氯化钠注射液＋注射用亚叶酸钙＋注射用5-氟尿嘧啶）、OLF组（注射用奥沙利铂＋注射用亚叶酸钙＋注射用5-氟尿嘧啶），运用药物经济学方法比较其成本-效果。3种方案药品成本分别为7071．0元、10238．4元、17365．5元；有效率分别为33．33％、34．29％、40．00％。在方案LF的基础上，每再获得1个单位效果，方案HDLF，OLF所需追加的成本分别为3299．38元、1543．40元。结果表明，3种方案中OLF为较佳治疗方案。The objective of the study was to investigate the economic effects of the three chemotherapeutic schemes in the treatment of advanced colorectal carcinoma. One hundred and six cases with advanced colorectal carcinoma were randomly divided into 3 groups：group LF,group HDLF and group OLF. The cost effectiveness of the 3 groups were compared by using the statistical method of pharmaceutic economics. As results,drug costs of the 3 schemes were ￥7071.0,￥10238.4 and ￥17365.5 respectively. And the effective rates of the 3 schemes were 33.33%,34.29% and 40.00% respectively. On the basis of scheme LF, scheme HDLF and scheme OLF might increase the costs of ￥3299. 38 and ￥1543.40 respectively for 1% increase of effective rate. It is concluded that scheme OLF is the preferred choice.

关 键 词：大肠肿瘤 化学药物疗法 成本-效果分析 

分 类 号：R735.34[医药卫生—肿瘤]