纳米载银无机抗菌剂对义齿基托树脂抗菌性能的影响  

Influence of Nano-Silver Base Inorganic Antimicrobial on Denture Base Resin

作　　者：佘文珺[1] 胡滨[1] 张富强[1] 

机构地区：[1]上海交通大学医学院第九人民医院口腔修复科上海市口腔医学研究所,上海200011

出　　处：《上海交通大学学报（医学版）》2006年第10期1096-1098,共3页Journal of Shanghai Jiao tong University:Medical Science

基　　金：上海市重点学科建设基金(T0202);上海市教育发展基金(200201)资助项目

摘　　要：目的研究纳米载银无机抗菌剂对义齿基托树脂抗菌性能的影响。方法纳米载银无机抗菌剂FUMAT T200-4，按0％（对照组）、1％、2％、3％、4％、5％、7％、10％（V／V）比例添加在加热固化型义齿基托树脂中。采用薄膜密着法检测抗菌剂对变形链球菌、白色念珠菌的抑菌作用，并分析比较抗菌剂添加比例与基托树脂抗菌性能的相关性。结果添加纳米载银无机抗菌剂的基托树脂对变形链球菌、白色念珠菌具有良好的抑菌作用。抗菌剂添加比例1％～10％组对变形链球菌的抑菌率分别为24．5％、73．3％、80．2％、87．2％、90．7％、96．5％、100％，对白色念珠菌的抑菌率分别为26．3％、46．7％、53．3％、63．1％、69．9％、73．2％、79．8％，抗菌性能随添加比例的上升而明显提高。结论纳米载银无机抗菌剂的添加赋予了基托树脂良好的抗菌性能。Objective To explore the influence of nano-silver base inorganic antimicrobial on denture base resin. Methods The experimental groups of denture base resin were mixed with the nano-silver base inorganic antimicrobial FUMAT T2004, whose incorporating doses were 0% （control） , 1% ,2% ,3% ,4% ,5% ,7% and 10% （V/V）. Antimicrobial properties against Streptococcus mutans and Candida albicans were assayed with the pellicle-sticking method. Results The experimental groups had good inhibitory effect on Streptococcus mutans and Candida albicans. The inhibition percents for Streptococcus mutans of each group （1% -10% ） were 24.5% , 73.3% , 80.2% , 87.2%, 90.7%, 96.5% and 100%, and those for Candida albicans were 26.3%, 46.7%, 53.3%, 63.1%, 69.9% , 73.2% and 79.8% , respectively. The antimicrobial properties of the denture base resin were strengthened with the increasing doses of the antimicrobial. Conclusion Denture base resin incorporated with nano-silver base inorganic antimicrobial enjoys good antimicrobial properties.

关 键 词：纳米载银无机抗菌剂 基托树脂 抗菌性能 

分 类 号：R783.1[医药卫生—口腔医学]