肿瘤相关物质群水平对鼻咽癌复发转移的诊断价值  

TSGF in monitoring recurrence and metastasis of nasopharyngeal carcinoma

作　　者：林高娟 刘陶文 

机构地区：[1]广西桂林市南溪山医院肿瘤一区,广西桂林541002

出　　处：《现代肿瘤医学》2006年第11期1367-1368,共2页Journal of Modern Oncology

摘　　要：目的:探讨肿瘤相关物质群(TSGF)对鼻咽癌复发转移的诊断价值。方法:采用比色法测定71例复发转移鼻咽癌患者及42例健康人的血清TSGF水平。结果:鼻咽癌患者血清TSGF水平(x-±s)显著高于健康对照组(68.7±14.1)U/ml vs(59.1±3.6)U/ml,P<0.01;肿瘤转移患者血清TSGF水平高于局部复发组(72.0±14.6)U/ml vs(64.7±12.6)U/ml,P<0.05,尤其是骨转移癌患者;以64U/ml为临界值时,TSGF检测复发转移癌的敏感性为70.4%(50/71)、特异性为95.2%(40/42)。结论:血清TSGF水平对鼻咽癌的监测具有高度敏感性、高度特异性,是监测其复发转移的重要指标。Objective：To determine the clinical diagnosis value of tumor supplies group of factors （TSGF） in the racurrence and metastasis of nasopharyngeal carcinoma. Methods： Serum TSGF level was determined by spectrophototometry in 71 patients with reourrence and metastasis of nasopharyngeal carcinoma and 42 healthy people as control. Results ： TSGF level （ x ± s ） in recurrent tumors was significantly higher than in healthy control group （68.7±14.1U/ml vs 59.1 ±3.6U/ml, P 〈0. 01 ）, compared with local recurrence, TSGF level was significantly elevated in patients with metastasis tumor（ 72.0±14.6U/ml vs 64.7 ±12.6U/ml, P 〈 0. 05 ）, especially with bone metastasis. Conclusion： TSGF assay is a methed with highly sensitivity and specificity for nasopharyngeal carcinoma, is an important marker in monitoring recurrence and metastasis of nasopharyngeal carcinoma.

关 键 词：恶性肿瘤 肿瘤相关物质群 复发 转移 肿瘤标志物 

分 类 号：R739.63[医药卫生—肿瘤]