围术期血液稀释与输异体血对肝癌病人红细胞免疫功的影响  

Effect of perioperative allogeneic and Acute blood dilution in equal-capability on erythrocyte immune function in patients with liver cancer

作　　者：谭立清[1] 黄中华[1] 张庆敏[1] 刘燕洁[1] 黄小彬[1] 秦丹丹[1] 

机构地区：[1]广西壮族自治区人民医院麻醉科,南宁530021

出　　处：《广西医学》2006年第11期1694-1695,共2页Guangxi Medical Journal

基　　金：广西科学基金课题(桂科自:9824003)

摘　　要：目的探讨术前等容血液稀释自身输血与输异体血对肝癌病人红细胞免疫功能的影响,方法20例肝癌病人,随机分为急性等容血液稀释组,输异体血组。分别于术前,术后24、48、72h,抽取静脉血测定C3b受体花环率(C3bRR)、红细胞免疫复合物(ICR)、红细胞免疫促进因子(FER)、红细胞免疫抑制因子(FIR)。结果两组病人术前红细胞免疫功能均低下,血液稀释组的红细胞的免疫功能术后24h即有所恢复,对照组在术后72h才恢复。结论围术期急性等容血液稀释自身输血对尽快恢复肝癌病人红细胞的免疫功能有帮助。objectives To investige effect of perioperative allogeneic or autologous blood transfusion on erythroeyte immune function in patients with liver eaneer.Methods 20 liver cancer patients were randomly divided into two groups with 10 patients in each group of autologous blood transfusion group（group Ⅰ ） amd allogenenic blood transfusion group （group Ⅱ ）. Blood sample were drawn with peripheral vein before operation and 24 h,48 h,72 h after operation to determine the count of C3 bRR, ICR, FER, FIR. Result Autologous transfusion group resume immune fuction in 24 h, but control group 72 h. Conclusions Perioperation autologous transfusion can help to resume erythroeyte immune fuction.

关 键 词：围术期急性等容血液稀释 输血 肝癌 红细胞免疫功能 T细胞亚群 

分 类 号：R735[医药卫生—肿瘤] R446.3[医药卫生—临床医学]