焦虑症患者Quisi监测的睡眠脑电特点  

Characteristics of sleep electroencephalography in anxiety disorder patients monitored by Quisi technique

作　　者：宗文斌[1] 路英智[1] 蒲金玉[1] 

机构地区：[1]淄博市精神病医院功能科,山东省淄博市255120

出　　处：《中国临床康复》2006年第42期16-17,共2页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:观察焦虑症患者Quisi监测的睡眠脑电图特点,以探讨Quisi在焦虑症辅助诊断中的价值及适应症。方法:于2004/2005选择淄博市精神病医院进行心理咨询就诊的焦虑症患者26例(汉密顿焦虑量表评分≥14分),正常对照组为来自本院的按照年龄、性别相匹配原则配伍的志愿者22人。应用德国Quisi仪,对所有受试者的睡眠脑电图进行连续2夜测试。测量的睡眠参数包括睡眠进程、睡眠结构和快速眼运动睡眠3个方面的15项指标(总记录时间、睡眠潜伏期、觉醒时间、睡眠总时间、觉睡比、睡眠效率、睡眠维持率、快速眼运动睡眠潜伏期、第1阶段百分比、第2阶段百分比、第3阶段百分比、第4阶段百分比、快速眼运动睡眠百分比、暂停百分比、伪迹百分比)。结果:26例焦虑症和22名正常人均收到完整的睡眠记录,全部纳入结果分析。①与正常对照组相比,焦虑症组出现睡眠潜伏期和觉醒时间增加([34.5±17.9),(23.9±17.4)min,t=2.0,P<0.05],[(39.8±21.9),(19.3±14.9)min,t=3.6,P<0.01];睡眠效率和睡眠维持率下降[(83.7±6.9)%,(93.3±5.1)%,t=5.29,P<0.01],([88.8±9.1)%,(99.8±4.9)%,t=5.7,P<0.01];快速眼运动睡眠潜伏期减少([69.9±16.3),(88.6±15.9)min,t=4.9,P<0.01];快速眼运动第2阶段睡眠百分比增加([55.3±11.9)%,(47.5±7.8)%,t=2.56,P<0.05];第3阶段睡眠百分比减少([8.9±6.9)%,(14.1±6.1),t=2.7,P<0.01];快速眼运动睡眠百分比减少([10.1±5.9)%,(16.9±5.1),t=4.1,P<0.01];伪迹百分比增加([3.9±1.3)%,(1.9±0.8)%,t=6.1,P<0.01]。②焦虑症组患者第1夜的睡眠潜伏期、觉醒时间、睡眠总时间、觉醒睡眠比、睡眠效率、睡眠维持率、快速眼运动睡眠潜伏期、第1～第4阶段百分比、快速眼运动睡眠百分比等指标与第2夜的差异均无显著性意义(P均>0.05)。结论:Quisi测量、记录的各项睡眠指标稳定、方便临床应用,特别适合于全夜监测。在不具备脑电监测技术的基层医�AIM： To observe the sleep electroencephalogram （EEG） of patients with anxiety disorder by Quisi, and further investigate the value and accommodation of Quisi in the diagnosis of anxiety. METHODS： Between 2004 and 2005, 26 patients with anxiety disorder （score of Hamihon Anxiety Scale ≥ 14 points） who received psychological consultations in the Fifth People＇s Hospital of Zibo were adopted in this study, meanwhile 22 volunteers matching the patients well in age and gender were taken as normal controls. All the subjects were tested for 2 continuous nights and recorded by sleep EEG of Germany Quisi Instrument. Sleep parameters included 15 items in 3 aspects： sleep process, sleep structure and rapid eye movement （REM） （total time of record, sleep laten- cy, time of awaking, total sleep duration, ratio of awaking to sleep, sleep efficiency, sleep maintenance, sleep latency of REM, percentages of sleep in stages 1, 2, 3 and 4, percentages of sleep, pause and artifact in REM）. RESULTS： A total of 26 patients and 22 controls completed records of sleep parameters and were involved in the result analysis. ①Compared with normal control group, the patients with anxiety disorder presented to increase the sleep latency and time of awaking [（34.5±17.9）, （23.9±17.4） minutes, t=2.0, P 〈 0.05; （39.8±21.9）, （19.3±14.9） minutes, t=3.6, P 〈 0.01], decrease the sleep efficiency and sleep maintenance [（83.7±6.9）%, （93.3±5.1）%, t=5.29, P 〈 0.01; （88.8±9.1）%, （99.8±44.9）%, t=5.7, P 〈 0.01], reduce the sleep latency of REM [（69.9±16.3）, （88.6±15.9） minutes, t=4.9, P 〈 0.01], elevate the percentage of sleep in stage 2 of REM [（55.3±11.9）%, （47.5 ±7.8）%, t=2.56, P 〈 0.05], lessen the percentage of sleep in stage 3 of REM [（8.9±6.9）%, （14.1±6.1）, t=2,7, P 〈 0.01], diminish the sleep percentage of REM [（10.1±5.9）%, （16.9±5.1）, t=4.1, P 〈 0.01], and heighten the artifact percentage of REM [（3.9±1.3）%, （1.9±0.

关 键 词：焦虑症 睡眠 快速眼运动 监测 生理学 

分 类 号：R749.72[医药卫生—神经病学与精神病学]