卵磷脂络合碘治疗外伤性黄斑出血的临床观察  

Clinical Study of Lecithin-bound Iodine in the Treatment of Traumatic Macular Hemorrhage

作　　者：马晓昀[1] 徐格致[1] 

机构地区：[1]复旦大学附属眼耳鼻喉科医院眼科

出　　处：《世界临床药物》2006年第11期653-656,共4页World Clinical Drug

摘　　要：目的评价卵磷脂络合碘治疗外伤性黄斑出血的临床疗效。方法随机将64例外伤性黄斑出血患者分为治疗组和对照组,每组32例32眼。对照组予卡巴克络(安络血)一日3次,每次500mg,连续服用20天。治疗组予卵磷脂络合碘(沃丽汀)一日3次,每次600μg,连续服用20天后减为一日3次,每次300μg,继续服用40天。在60天的随访期内分别观察视力及黄斑出血、水肿的变化以及并发症,并行统计分析。结果治疗组平均治愈时间短于对照组,视力恢复情况优于对照组。两组相比差异具有统计学意义(P<0.05)。结论卵磷脂络合碘有助于黄斑出血、水肿的吸收及视功能的改善,用于外伤性黄斑出血治疗可取得较好的临床疗效。Objective To evaluate the clinical effect of lecithin-bound iodine in the treatment of traumatic macular hemorrhage. Methods 64 eyes of 64 cases suffering from traumatic macular hemorrhage were randomized divided into two groups, the observer group （n=32） and the control group （n=32）. The observer group was administered carbazochrome 500mg three times per day for 20 days.The control group was administered lecithin-bound iodine 600pg three times per day for 20 days first, and then 300pg three times per day for 40 days.Changes of visual acuity, macular hemorrhage, macular edema and other complications were examined in the period of 60 follow-up days. Result The recover time of control group was shorter than that of observer group, the final visual acuity of control group was better than that of observer group, and the difference between two groups was statistically significant （P〈0.05）. Conclusion Lecithin-bound iodine conduced to the absorption of macular hemorrhage and edema and the improvement of visual acuity. It is efficacious in the treatment of traumatic macular hemorrhage.

关 键 词：卵磷脂络合碘 挫伤 黄斑 出血 

分 类 号：R774.5[医药卫生—眼科]