胶原、壳聚糖及其共混膜对红细胞的影响  

Influence of Chitosan,Collagen,Collagen/Chitosan Films on Red Blood Cells

作　　者：梁志红[1] 周长忍[2] 林潮平[1] 洪爱华[1] 李国强[1] 

机构地区：[1]暨南大学实验技术中心 [2]暨南大学材料系,广东广州510632

出　　处：《高分子材料科学与工程》2006年第6期161-164,共4页Polymer Materials Science & Engineering

基　　金：国家自然科学基金(30271370);广东省重点项目(3001A30202010)资助项目

摘　　要：利用原子力显微镜高分辨、低损伤的成像能力,研究比较了壳聚糖膜(CSF)、胶原膜(COF)、胶原/壳聚糖共混膜(COF/CSF)对红细胞的影响。结果显示,壳聚糖膜对红细胞的粘附、聚集作用明显,导致红细胞形态异常甚至碎裂。胶原膜上的红细胞外形不规则,但细胞无碎裂。共混膜对红细胞有一定的粘附作用,对细胞形态的影响程度界于两种单组分膜之间。The influence of chitosan, collagen, collagen/chitosan films on red blood cells was investigated by AFM. The experimental results show that red blood cells adheres and coagulates obviously to chitosan films, accompanying with cellular abnormal in shape. The cells change smoothly in shape on collagen films. The degree of the influence of collagen/chitoson films on red blood cells are lower than chitosan films but higher than collagen films.

关 键 词：胶原膜 壳聚糖膜 胶原/壳聚糖共混膜 红细胞 原子力显微镜 

分 类 号：TB383[一般工业技术—材料科学与工程]