产痛与产后抑郁症的相关性研究  

Study of the Interrelation Between Labor Pains and Puerperal Depression State

作　　者：尹春艳[1] 张智[1] 陈健飞[1] 李泽泳[1] 陈晓艳 陈月秀 刘婷婷 

机构地区：[1]广东省第二人民医院,广东广州510317 [2]广州市天河区红会医,广东广州514023 [3]广州市新海医院,广东广州510300 [4]广州市新窖人民医院,广东广州510321

出　　处：《中国实用医药》2006年第1期8-10,58,共4页China Practical Medicine

基　　金：广东省医学科研基金资助课题(A2004518)。;广东省自然基金资助项目(040005053)。

摘　　要：目的探讨产痛与产后抑郁症的相关性。方法2005年8月～11月广东省第二人民医院采用硬膜外阻滞分娩镇痛并阴道分娩的初产妇121例为实验组,同期未采取任何分娩镇痛技术的其他3家医院阴道分娩的初产妇97例为对照组,在第3产程未和产后7d进行雌二醇(E2)、孕酮(P)、催乳素(PRL)监测;产后3d和产后7d进行EPDS评分。结果实验组与对照组比较:第3产程未E2、P水平差异有显著性(P<0.05～0.001),PRL水平差异无显著性(P>0.05);产后7dE2、P、PRL水平差异均有显著性(P<0.05～0.001)。组内比较:两组第3产程未与产后7dE2、P水平差异极其显著(P<0.00),PRL水平差异无显著性(P>0.05)。实验组产后3d、7dEPDS评分和产后抑郁症发生率比较明显低于对照组(P<0.02～0.05)。结论产痛是导致产后抑郁症生物-心理-社会学基础的统一体,提倡分娩镇痛是减少产后抑郁症发病率的重要途径之一。Objective To explore the interrelation between labor pains and puerperal depression state.Methods 121 parturient accepting epidural block anesthesia of labor in the second people＇s hospital of Guangdong province from August, 2005 to November, 2005 were chosen as the experimental group, 97 parturient not accepting any anesthesia of labor in other three hospitals at the same time as the control group. Monitored the numerical value of E2, P and PRL at the end of the third stage of labor and the postpartum seventh day. Made EPDS scores in the postpartum third day and postpartum seventh day.Results At the end of third stage of labor, there were significant difference in the level of E2 and P （P〈0.05-0.01） between the two groups; there was no significant difference in the level of PRL （P〉0.05）; there were significant difference in the level of E2, P and PRL in the postpartum seventh day （P〈0.05-0.001）. In the experimental group, at the end of the third stage of labor and the postpartum seventh day, there were significant differences in the levels of E2 and P（P〈0.00） between the two groups; while there was no significant difference in the level of PRL （P〉 0.05）. Scores of EPDS and the incidence of puerperal depression state in the experimental group were significantly lower than those in the control group （P〈0.02-0.05）.Conclusion Labor pains result in puerperal depression state that was a unity of organism, psychology and the basis of sociology. Anesthesia of labor is one of the important ways to decrease the incidence of puerperal depression state.

关 键 词：产痛 产后抑郁症 分娩镇痛 

分 类 号：R749.4[医药卫生—神经病学与精神病学] R714.7[医药卫生—临床医学]