中药马钱子中毒死亡检验方法的研究  

Determination by GC-NPD and GC-MS of Traditional Chinese Medicine of Semen Strychnine

作　　者：段韵[1] 姜燕[2] 符芸[1] 王洪宗[3] 刘勇孜[3] 

机构地区：[1]江西省人民医院药剂科,南昌330006 [2]南昌大学第二附属医院药剂科,南昌330006 [3]江西省公安厅,南昌330006

出　　处：《中国药学杂志》2006年第21期1616-1618,共3页Chinese Pharmaceutical Journal

摘　　要：目的建立人体生物检材中的士的宁和马钱子碱的检测方法。方法用GC/NPD及GC/MS检测马钱子药渣,喝剩的马钱子药液及人体肝脏中士的宁和马钱子碱。结果建立了多种样品中士的宁和马钱子碱的定性、定量分析方法。结论本方法操作简便,定性定量准确,可靠。用此方法可以准确测定生物检材(肝脏等)的士的宁和马钱子碱含量。OBJECTIVE To establish the determination method of strychnine and vauqueline in biological materials such as drug residues, the remaining drug solution and human liver. METHOD The GC-NPD and GC-MS was used to determine the contents of strychnine and vauqueline. RESULT A reliable quantitative and qualitative determination method was established. CONCLUSION The method can be used to determine strychnine and vauqueline in biological materials （in liver et al）.

关 键 词：士的宁 马钱子碱 气相色谱氮磷检测器 气相色谱-质谱 定性定量分析 

分 类 号：R284[医药卫生—中药学]