BioSun2.0:一个综合性的辅助分子生物学实验设计软件  

BioSun2.0:a comprehensive software for molecular biology experiments

作　　者：查磊[1] 应晓敏[1] 曹源[1] 李华[1] 李伍举[1] 

机构地区：[1]军事医学科学院基础医学研究所计算生物学中心,北京100850

出　　处：《军事医学科学院院刊》2006年第5期461-464,共4页Bulletin of the Academy of Military Medical Sciences

基　　金：国家自然科学基金项目(30470411);北京市自然科学基金项目(5042021)

摘　　要：我们曾于2004年推出了计算机辅助分子生物学实验设计的软件系统B ioSun 1.0,该系统提供了较为全面的数据处理与分析功能。为了更好地服务于生物医学工作者,我们对该软件系统进行了升级,推出了2.0版本,新增的功能主要有:基于B last的多种形式的序列比对、基于C lustalW的多序列比对与进化树构建、蛋白质三维结构展示、基于RNA fold的RNA二级结构预测和序列格式转换等。通过与商业化综合性的生物信息学软件系统DNA-SIS MAX 2.05、DNAStar 5.0、Vector NTI 9.1和B ioEd it 7.0的比较发现,B ioSun2.0具有操作简便、功能众多和性价比高等特点,能够满足生物医学实验室的常规需求。BioSun1.0 was released by in 2004. It is a comprehensive bioinformatics software of computer-aided design of molecular biology experiments. In order to provide better tools for biomedical scientists, the BioSun have been updated recently to version 2.0. The functions such as Blast-based comparison, multiple sequence alignments, construction of phylogenic tree, 3D representation of a protein, RNA secondary structures prediction, sequence format conversion and others were added in the new version. Finally, a detailed comparison of BioSun2.0 with the commercial software, which includes DNASIS MAX 2.05, DNAStar 5.0, Vector NTI 9.1 and BioEdit 7.0 was provided. The results show that BioSun2.0 has the characteristics such as easy operation, multiple functions, and high quality/price ratio, and can fulfill the common requirements of biomedical Labs.

关 键 词：BioSun 生物信息学 计算机辅助设计 

分 类 号：Q7-3[生物学—分子生物学]