152例老年大肠癌临床病理学特征与预后  

Clinical pathological features in 152 cases of elderly patients with colorectal cancer

作　　者：陈静[1] 杨大业[1] 张德巍[1] 孙玉华[1] 梁健[1] 

机构地区：[1]中国医科大学附属第四医院普外科,辽宁沈阳110005

出　　处：《中国医学工程》2006年第5期538-540,共3页China Medical Engineering

摘　　要：目的探讨老年人大肠癌的临床病理学特征与预后。方法总结1993年7月～2000年12月间收治的65岁以上老年人大肠癌152例,分析其临床特点、病理学特征和生存率。结果152例老年人大肠癌中,合并其他疾病者101例(66.5%);Dukes分期:B、C期116例(76.3%)。病理类型:腺癌131例(86.2%),其中高、中分化腺癌83例,低分化腺癌48例;黏液腺癌13例(8.5%);印戒细胞癌3例(2.0%);息肉恶变5例(3.3%);合并大肠息肉25例(16.4%);多原发性大肠癌2例(1.3%);术后1年生存率90.2%,3年生存率76.8%,5年生存率55.4%。结论目前老年大肠癌发病率逐渐增高,临床分期以进展期为主,病理类型主要为高、中分化腺癌,手术根治率高,预后较好,但应注意合并大肠息肉及多发原发性大肠癌的发生。[Objective] To discuss the clinical pathological feature and prognosis in 152 cases of elderly patients with colorectal cancer. [Methods] We analyzed the clinical pathological feature and survival rate of colorectal cancer patients whose age were 65 years or above from July 1993 to December 2000. [Results] Comorbidities were 101 cases in 152 cases elderly patients. Dukes stages B and C were noted in 116 cases （76.3%）. The proportion of adenocarcinoms was 86.2%（131/152）, Mucinous carcinoma was 8.5%（13/152）, signet-ring cell carcinoma was 2.0% （3/152） and polypi canceration was 3.3%（5/152）. The proportion of accompanied polypi was 16.4% （25/152） and multiple primary colorectal cancer was 1.3%（2/152）. The 1-year survival rate was 90.2%, the 3-year survival rate was 76.8% and the 5-year survival rate was 55.4%. [Coulusion] At present elderly patients with colorectal cancer have a high Morbidity ,many comorbidities,a high proportion of advenced stage and moderately and well-differentiated adencarcinoma in pathological classitication,a high complete resection rate and good prognosis.But accompanied polypi and multiple primary colorectal carcinoma should be attentioned.

关 键 词：大肠癌 老年人 病理 

分 类 号：R735.34[医药卫生—肿瘤]