A Comparative Study of Mass Screening Findings for Prostate Cancer between Changchun in China and Natori in Japan  

作　　者：Hongliang Wang Ling Zhang Chunxi Wang Haifeng Zhang Ning Xu Guoyi Ji Xiaomeng Li Hongwen Gao Xuejian Zhao 

机构地区：[1]Department of Pathophysiology, College of Basic Medicine, Jilin Universety Main research field： procreated pathophysiology i Department of Urology, Jilin University First Hospital, Changchun, 130041 [2]Prostate Diseases Prevention and Treatment Research Center, Jilin Universety, Changchun,130021

出　　处：《Journal of US-China Medical Science》2006年第2期5-8,共4页美中医学（英文版）

摘　　要：Objective A mass screening in China＇s Changchun City and Japan＇s Natori City was conducted respectively with a view to making a comparison of the incidence status and clinic condition of prostate cancer between the two cities concerned. Methods 3566 Chinese and 2212 Japanese men older than 55 years old were mass checked by PSA-based screening, and those whose serum PSA elevated 4.0 ng/ml also underwent ultrasound-guided sextant prostatic biopsies. Results （1） In Changchun City, the PSA-positive rates （PSA 4.0 ng/mL or more） was 5.2% （185 in 3566）, a little lower than 8.5% （189 in 2212） in Natori City. （2） Cancer detection rate in the screened persons in Changchun was 0.8% （28 in 3566）, much lower than 2.1% （46 of 2212） in Natori. （3） The cancer detection rate by prostate biopsy was 25.2% （28 of Ⅲ） in Changchun and 26.9% （46 of 171） in Natori. （4） The number and percentage of cases of clinical stage Ⅱ and Ⅲ＋Ⅳ were 17 （61%） and 11 （39%） in Changchun and 30 （65%） and 16 （35%） in Natori. （5） Seen in terms of the histologic grading, the rate of poorly and middle differentiated cancer was higher in Changchun （89%）, while the percentage of well and middle differentiated cancer was higher in Natori （76.5%）. Conclusion （1） Mass screening for prostate cancer is the best approach to early diagnosis and treatment of prostate cancer. （2） The analysis of the results suggests that the prostate cancer incidence and prevalence in Changchun, China are lower than those in Natori, Japan. （3） The histologic grade percentage of poorly differentiated cancer in Changchun is higher than that in Natori.

关 键 词：prostate-specific antigen （PSA） prostate cancer clinical stage histologic grading 

分 类 号：R737.2[医药卫生—肿瘤]