Pentacam系统与A超角膜测厚仪测量瞳孔中心角膜厚度的比较  

Measurement of central corneal thickness in myopic eyes with ultrasound and Pentacam scheimpflug system

作　　者：何燕玲[1] 黎晓新[1] 鲍永珍[1] 刘国栋[1] 胡亦文[1] 

机构地区：[1]北京大学人民医院眼科,100044

出　　处：《中华眼科杂志》2006年第11期985-988,共4页Chinese Journal of Ophthalmology

摘　　要：目的比较Pentacam三维眼前节分析诊断系统与A型超声角膜测厚仪在正常人与近视眼患者瞳孔中心角膜厚度的测量结果,为临床使用提供依据。方法首先对正常人50只眼连续进行3次Pentacam系统检查,以评价该系统对角膜厚度测量的重复性。进而选取217例(433只眼)拟行准分子激光原位角膜磨镶术(LASIK)的屈光不正患者和LASIK术后6个月以上患者63例(126只眼),分别应用Pentacam系统和A超进行角膜厚度测量,并对检查结果进行统计学分析。结果50只正常眼瞳孔中心角膜厚度重复测量结果差异无统计学意义(P>0.05),表明Pentacam系统检查结果重复性很好。在对角膜厚度的测量结果中,术前A超测厚和Pentacam系统测量的瞳孔中央角膜厚度分别为(537.26±31.61)和(538.08±32.72)μm,术后分别为(464.21±41.04)和(465.17±42.65)μm,术前后两种测量方法的结果之间差异均无统计学意义(P>0.05),两种测量结果之间具有密切的线性相关(P<0.001),其中术前两种仪器测量结果的差值在20μm以内的达95.38%。角膜最薄点多位于距角膜顶点周围1mm范围内稍偏颞下方。结论用Pentacam三维眼前节分析诊断系统进行LASIK术前后角膜厚度的测量,结果准确、全面、方便,具有较好的临床应用价值。(中华眼科杂志,2006,42985-988)Objective To assess the accuracy and variability of central corneal thickness measurements in myopic eyes obtained by ultrasound pachymetry and the Pentacam scheimpflug imaging system. Methods First, corneal thickness in 50 healthy eyes was measured three times with the Pentacam system to evaluate the repeatability. Then, Scheimplug imaging system （Pentacam） and A-scan ultrasonic pachymeter （SP-3000） were used to measure the corneal thickness on 217 myopic cases （433 eyes ） undergoing laser in situ keratomileusis （LASIK） and 63 cases （ 126 eyes） 6 months after LASIK. The results were compared. Results Repeated-measures ANOVA showed the repeatability of the Pentacam measurements was high （ P 〉 0. 05 ）. Pre-operatively, the value of corneal central thickness measured by ultrasonic pachymetry and the Pentacam system was （537.26 ±31.61） μm and （538.08 ±32.72） μm, respectively. There was no significant difference between the results of these two methods （ t = 1. 867, P 〉 0. 05 ）. The difference between these two methods ranged - 35 - 34 μm, and was within - 20 - 20 μm in 95.38% cases. Post-operatively, the value of corneal central thickness measured by ultrasonic pachymetry and the Pentacam system was（464. 21 ±41.04） μm and（465. 17 ±42. 65） μm, respectively. There was no significant difference between these two methods, too （t = 0. 913, P 〉 0. 05 ）. There was a significant linear correlation between the two methods （ P 〈 0. 001 ） . The thinnest point of cornea was mostly located surrounding the apex and inclined towards inferotemporal. Conclusion The Pentacam scheimpflug system offers an acceptable method for evaluating corneal pachymetry, which is useful in corneal refractive surgery.

关 键 词：角膜 超声检查 体层摄影术 光学 

分 类 号：R770.4[医药卫生—眼科] R779.63[医药卫生—临床医学]