Toxicities of p-nitrotoluenes and their effects on blood corpuscles and ovaries in Crusian carps (Carassius auratus)  

作　　者：匡少平 宋峰 

机构地区：[1]Qingdao University of Science and Technology

出　　处：《Chinese Journal Of Geochemistry》2006年第4期373-377,共5页中国地球化学学报

基　　金：The study is financially supported by the Development Foundation ofScience and Technology under Shandong Provincial Education Department(No. J05D51).

摘　　要：p-nitrotoluene is an important organic intermediate widely used in pesticide, foamed plastics, dyestuff and medicine industries. In this paper, Crusian carps (Carassius auratus) were exposed to dilute p-nitrotoluene solutions with different concentrations of 0, 20, 40, 80, 120, 160, 240 and 320 μg/L; the subsequent physiological responses to the chemical were observed, and the variation characteristics of blood corpuscles, ovaries and oocytes were studied by bio-microscopy. Results showed that even very low concentrations of p-nitrotoluene would lead to toxicosis and even the death of Carassius auratus. The bio-microscopic structures revealed that, compared with the compartment of Carassius auratus growing in the p-nitrotoluene–free water (the control group), the lower concentrations of p-nitrotoluene (for example no more than 80 μg/L) would result in the faster disintegration of erythrocytes and the significant enlargement of oocytes, while the higher contents of p-nitrotoluene (no less than 240 μg/L in this case) would inhibit the division of cells and their further growth, even degenerate blood corpuscles and ovaries, suggesting stronger estrogenic activities.p-nitrotoluene is an important organic intermediate widely used in pesticide, foamed plastics, dyestuff and medicine industries. In this paper, Crusian carps （Carassius auratus） were exposed to dilute p-nitrotoluene solutions with different concentrations of 0, 20, 40, 80, 120, 160, 240 and 320μg/L; the subsequent physiological responses to the chemical were observed, and the variation characteristics of blood corpuscles, ovaries and oocytes were studied by bio-microscopy. Results showed that even very low concentrations of p-nitrotoluene would lead to toxicosis and even the death of Carassius auratus. The bio-microscopic structures revealed that, compared with the compartment of Carassius auratus growing in the p-nitrotoluene-free water （the control group）, the lower concentrations of p-nitrotoluene （for example no more than 80 μg/L） would result in the faster disintegration of erythrocytes and the significant enlargement of oocytes, while the higher contents of p-nitrotoluene （no less than 240 μg/L in this case） would inhibit the division of cells and their further growth, even degenerate blood corpuscles and ovaries, suggesting stronger estrogenic activities.

关 键 词：血细胞 卵巢 卵细胞 p-硝基甲苯 环境激素 

分 类 号：X174[环境科学与工程—环境科学]