薯蔓总黄酮的免疫调节作用  

The Study of Immunoregulation Effect of FSPV

作　　者：罗丽萍[1] 高荫榆[1] 熊绍员 洪雪娥[1] 夏冬华[1] 

机构地区：[1]南昌大学食品科学教育部重点实验室,江西南昌330031 [2]江西省植保植检总站,江西南昌330046

出　　处：《南昌大学学报（理科版）》2006年第5期489-491,共3页Journal of Nanchang University(Natural Science)

基　　金：江西省科技厅农业重大基金资助项目(20041A0500103)

摘　　要：研究薯蔓总黄酮(FSPV)的非特异性免疫和特异性体液免疫调节作用。采用碳粒廓清实验研究了FSPV对正常和免疫低下小鼠的非特异性免疫功能;血清溶血素测定法研究了FSPV的特异性体液免疫功能。FSPV可提高正常和免疫低下小鼠的廓清指数K和呑噬指数α,尤其是400 mg/kg剂量可使廓清指数极显著升高(P<0.01);实验所用剂量的FSPV对小鼠的血清溶血素HC50无显著影响。FSPV具有促进单核巨噬细胞系统吞噬功能的作用,可增强小鼠的非特异性免疫功能,但对小鼠的特异性体液免疫功能无显著影响。To investigate the immunoregulation effect of FSPV. By using carbon particle clearance test to study the nonspecific immunological function of FPSV on normal and immunosuppression mice. By using the hemolysin test to study the specific humoral immunological effect of FSPV on normal mice. The carbon particle clearance index and phagocytic index of normal and immunosuppression mice is increased by giving FSPV to the mice. Especially when the dose is 400mg/kg,the carbon particle clearance is increased remarkably （P 〈 0.01 ）. FSPV has no significant influence on HC50. FSPV has potent enhancement on non - specific immunity of mice. But it has no remarkable influence on the humoral immunity.

关 键 词：薯蔓 黄酮类化合物 免疫调节作用 非特异性免疫 特异性体液免疫 

分 类 号：R967[医药卫生—药理学]