大肠癌淋巴结转移预测模型的建立  

Establishing A Mathematical Model to Predicting Lymphatic Node Metastasis in Colorectal Cancer

作　　者：李力人[1] 万德森[1] 潘志忠[1] 周志伟[1] 

机构地区：[1]华南肿瘤学国家重点实验室,中山大学肿瘤防治中心,广东广州510060

出　　处：《中国肿瘤》2006年第12期876-878,共3页China Cancer

基　　金：广东省医学科学研究基金(B2005050)

摘　　要：[目的]建立数学模型预测和发现淋巴结转移的高危人群。[方法]回顾性分析1990年1月至1999年12月施行根治性切除的1051例大肠癌,并建立预测淋巴结转移的数学模型。[结果]预测大肠癌淋巴结转移的数学模型:淋巴结转移=-2.248-0.017×年龄-0.671×家族史+0.437×部位+0.508×病理分级+0.395×浸润深度。[结论]利用临床病理学参数建立的数学模型可以预测和发现有淋巴结转移倾向的高危人群。[Purpose] To establish a mathematical model to predicting and discovering high risk colorectal cancer with lymphatic node metastasis, [Methods ] One thousand and fifty-one cases with colorectal cancer underwent radical resection between January, 1990 and December, 1999 were retrospectively analyzed and a mathematical model for predicting lymphatic node metastasis was established. [Results ] The mathematical model for predicting lymphatic node metastasis was following： lymphatic node metastasis = -2.248-0.017xage-0.671xfamily history＋ 0.437xtumor site＋0.508xcellular differentiation＋0.395xinvasive depth. [Conclusion] High risk population with lymphatic node metastasis in colorectal cancer could be predicted and discovered by using the mathematical model clinicopathological parameters.

关 键 词：结肠直肠肿瘤 淋巴转移 临床病理学 预测模型 

分 类 号：R735.34[医药卫生—肿瘤]