β-环糊精与N,N′-二(4-吡啶基甲基)-1,6-己二胺自组装包结行为的研究  

Investigation of the Self-assembled Inclusion Behaviour of β-Cyclodextrin and N,N-Bis(4-pyridylmethyl)-1,6-hexanediamine

作　　者：王志斌[1] 赵敏[1] 梁中伟[1] 陈慧兰[1] 

机构地区：[1]南京大学化学系配位化学重点实验室,南京210093

出　　处：《化学学报》2006年第23期2384-2388,共5页Acta Chimica Sinica

基　　金：国家自然科学基金(Nos.20071017.50272029)资助项目.

摘　　要：以4-吡啶甲醛和1,6-己二胺为原料,合成了含吡啶基的还原双席夫碱客体N,N′-二(4-吡啶基甲基)-1.6-己二胺(C6N4),通过核磁共振技术研究了β-环糊精与C6N4的自组装包结作用,测定了包结比和稳定常数．结果表明,β-环糊精与客体C6N4在水溶液中形成1∶1的包结配合物,其稳定常数的平均值为1．7×102dm3·mol-1．A reduced bis-Schiff base guest containing pyridyl, N,N＇-bis（4-pyridylmethyl）-1,6-hexanediamine （C6N4）, has been synthesized from 4-pyridinecarboxaldehyde and 1,6-hexanediamine. The self-as- sembled inclusion behaviour of β-cyclodextrin and linear guest C6N4 has been investigated by IH NMR. Our experimental results revealed that a 1 ： 1 inclusion complex of fl-cyclodextrin and C6N4 could be formed in aqueous solution and the average value of stability constant of inclusion complex was determined to be 1.7× 10^2 dma·mol^-1.

关 键 词：Β-环糊精 还原双席夫碱 包结作用 核磁共振技术 

分 类 号：O631.5[理学—高分子化学]