保乳手术切缘阳性的临床病理学因素分析  

Clinicopathologic analysis of positive resectional margin in breast conservative surgery

作　　者：李刚[1] 冯立民[1] 孙宪春[1] 乔广东[1] 朱世光[1] 吉田和弘[2] 

机构地区：[1]山东烟台市毓璜顶医院肿瘤外科,山东烟台264000 [2]日本广岛大学原医研肿瘤外科

出　　处：《外科理论与实践》2006年第6期504-506,共3页Journal of Surgery Concepts & Practice

摘　　要：目的:探讨保乳手术切缘阳性的相关临床病理学因素。方法:总结305例作保乳手术的乳腺癌病例,对保乳手术术中快速病理结合术后病理切缘阳性的结果进行分析。结果:保乳手术切缘阳性与病人年龄(≤35岁)、广泛导管内成分(EIC)、浸润性小叶癌等因素有关(P<0.05)。结论:在行保乳手术时,术中应详细检查切缘状况,对年轻病人、具广泛导管内成分、浸润性小叶癌者,须慎重选择保乳手术及切除范围的设定。Objective To explore the clinicopathologic features of positive resectional margin in breast conservative surgery. Methods From January 1998 to December 2003, 305 cases of stage I and H breast cancer were treated by breast conservative operation. The relationship between the clinicopathologic characteristics of the tumor and the resectional margin status was analyzed. Results The positive resectional margin was related to the young age of the patient （〈~35）, cases of extensive intra-ductal component （EIC） and invasive lobular carcinoma （P〈0.05）. Conclusions The status of the resectional margin should be examined carefully during breast conservative operation. For cases under the age of 35, those with EIC, or with the pathological type of invasive lobular carcinoma, breast conservative operation should be selected carefully, and planned with scrutiny.

关 键 词：乳腺肿瘤 保乳手术 临床病理学 

分 类 号：R737.9[医药卫生—肿瘤]