卵巢外腹膜浆液性乳头状癌的临床及病理学分析  

ExtraovarianPeritonealSerousPapilaryCarcinoma:StudiesofClinicalandPathologicalFeatures

作　　者：石雪君[1] 郭燕燕[1] 李竞贤[1] 汤秀英[1] 张莹 尹玲[1] 

机构地区：[1]北京医科大学第一医院病理科

出　　处：《中华妇产科杂志》1996年第12期711-713,共3页Chinese Journal of Obstetrics and Gynecology

摘　　要：目的：分析卵巢外腹膜浆液性乳头状癌的临床及病理学特点。方法：自１９８０年至１９９４年诊治的８１例卵巢浆液性乳头状癌中，选择其中１０例卵巢间质无肿瘤恶性浸润或仅累及卵巢表面上皮，而腹膜有广泛病变的卵巢外腹膜浆液性乳头状癌，对其进行回顾性分析，并进行组织高碘酸－希夫（ＰＡＳ）、奥辛蓝染色，应用免疫组织化学方法检测癌胚抗原（ＣＥＡ）、细胞角蛋白单克隆抗体ＡＥ１、ＡＥ３及电镜检查。结果：本组患者发病年龄为４６～７７岁，平均５７．９岁。患者双侧卵巢及输卵管正常。肿瘤病理形态与卵巢浆液性乳头状癌相似。ＰＡＳ、奥辛蓝染色及ＣＥＡ、ＡＥ１、ＡＥ３均为阳性。结论：卵巢外腹膜浆液性乳头状癌是原发于腹膜间皮苗勒管源性的恶性肿瘤。Objective:Tostudytheclinicopathologicalfeaturesofextraovarianperitonealserouspapilarycarcinoma(EPSPC).Methods:Theclinicalpicturesandpathologicalcharacteristicsof10casesofEPSPCadmittedtoourhospitalfrom1980through1994werestudiedretrospectively.Mean-while,controlstudieswereperformedfor5casesofovarianserouspapilarycarcinomaand4casesofmalignantperitonealmethothelioma.Results:Theagesofthe10patientswerebetween44and77.Thebilateraloveriesandfalopiantubeswerealnormal.Thehistomorphologyasexaminedbypho-tomicroscopeandultrastructuralelectromicroscope,thehistochemistrydeterminedbyperiodicacid-schif(PAS)andAlcianbluestainandtheimmuno-histochemistrydetectedbycarcinoembryonicantigen(CEA),AE1andAE3monoclonalantibodyassaysalrevealednodifferencebetweenEPSPCandovarianserouspapilarycarcinoma.ThesameistrueforthosebetweenEPSPCandmalignantmethotheliomaofperitoniumexceptthattheAlcianbluestainresultwouldturnedtobenegativefrompositiveafterdigestingwithhyaluronidaseandthemicro-viliarelongerformalignantperitonealmethotheliomaascomparedwithEPSPC.Conclusions:ThepathohistogenicityofEPSPCisnotfromovariesbutthemethotheliumofperitoneum,socaledthesecondaryMülariansystem.

关 键 词：腹膜肿瘤 浆液怀乳头状癌 病理学 卵巢外 

分 类 号：R735.502[医药卫生—肿瘤]