微创植入放射性粒子近距离治疗肿瘤的临床研究  

Study on the radioactive particle implantation in tumor brachytherapy.

作　　者：李挺[1] 姚波[2] 韦长元[1] 张支农 赫军[4] 

机构地区：[1]广西医科大学附属肿瘤医院,南宁530021 [2]柳州市中医院 [3]湖南湖湘中医肿瘤医 [4]广西中医学院一附院

出　　处：《微创医学》2006年第2X期78-81,共4页Journal of Minimally Invasive Medicine

基　　金：广西自然科学基金资助项目（桂科基0575064）

摘　　要：目的 总结8家医院对放射性粒子近距离治疗各种肿瘤的疗效，探索其治疗肿瘤的可行性。方法 采用CT、B超定位经皮穿刺、窥镜植入、术中种植放射性粒子等方法，对1013例肿瘤的1336个病灶共植入^125I28914粒、^103Pd457粒。并对407例肿瘤患者同时进行组织间化疗。结果 放射性粒子近距离治疗各种肿瘤后，局部控制率为97．60％，联合组织间化疗组的局部控制率为99．10％，病人1年生存率为90．50％，2年生存率为82．50％．并发症小于6％。结论 放射性粒子近距离治疗各种肿瘤效果明显，为一种新的微创治疗肿瘤的手段。Objective To summarize the effect of radioactive particle implantation in brachytherapy for different kinds of tumors in 8 hospital, and explore the feasibility of the therapy. Methods All the patient＇s were treated with percutaneous implantation and radioactive particle implantation in the operation guided by ultrasound and CT. 28 914 ^125I-seeds and 457 ^103Pd-seeds were implanted in 1 336 lesions of 1 013 cases, and interstitial chemotherapy was performed in 407 cases of tumor simultaneously. Results After treatment, the total local control rate was 97.6%, the local control rate in interstitial chemotherapy group was 99.1%, the one-year and two-year survival rates were 90. 5% and 82.5% respectively, the complication rate was less than 6%. Conclusion The radioactive particle implantation in tumor brachytherapy is a new, effective and minimally invasive therapy.

关 键 词：放射性粒子 肿瘤 靶区植入 

分 类 号：R730.5[医药卫生—肿瘤]