被动吸烟对健康青年人血管内皮舒张功能的影响  

Influence of passive smoking on dilatation function of vascular endothelial cells in the healthy young-adult

作　　者：刘爱玲[1] 马红[2] 王志凯[3] 田鹏[3] 王旺河[3] 

机构地区：[1]解放军第153中心医院特诊理疗科,郑州市450042 [2]武警河南总队医院特诊科 [3]河南省人民医院微创外科中心

出　　处：《实用诊断与治疗杂志》2006年第12期859-860,865,共3页Journal of Practical Diagnosis and Therapy

基　　金：河南省科技攻关计划项目0496410036

摘　　要：目的:探讨被动吸烟对健康青年人血管内皮舒张功能的影响。方法:采用超声肱动脉内径测量法,观察被动吸烟、主动吸烟及正常对照者各30例血流介导的和硝酸甘油介导的肱动脉内径变化。结果:三组肱动脉内径基础值及硝酸甘油介导的肱动脉舒张均无统计学意义(P>0.05),而血流介导的血管扩张被动吸烟组与正常对照组相比差异有统计学意义(P<0.01),与吸烟组相比无统计学意义(P>0.05)。结论:被动吸烟与健康青年人血管内皮舒张功能损伤有关,预示有早期动脉硬化损害。Objective To discuss the effects of passive smoking on dilatation function of vascular endothelial cells in the healthy young-adults. Methods Brachial artery internal diameters were measured by ultrasound to observe the changes of brachial artery internal diameters with flow-mediated and nitroglycerin induced in passive smoker group, active smoker group, and control group （30 cases each）. Results There was no significant difference in brachial artery basic internal diameters and brachial artery dilatation by nitroglycerin induced among three groups （P〉0.05）. Changes of brachial artery internal diameters by flow mediated were significantly different between passive smoker group and control group （P〈0.01）, while not significantly different between passive smoker group and active smoker group（P〉0.05）. Conclusion Passive smoking is related to the damage of vascular endothelial dilatation function of healthy young-adult, indicating earlier angiosclerosis.

关 键 词：高频超声 被动吸烟 吸烟 血管 内皮 舒张功能 

分 类 号：R363[医药卫生—病理学]