老年冠心病患者的血清尿酸水平分析  

Analysis of the relationship between severity degree of coronary lesions and hyperuricemia in elderly patients

作　　者：邓金龙[1] 熊莉芸[2] 林英忠[1] 王风[1] 覃绍明[1] 金献萍[1] 

机构地区：[1]广西壮族自治区人民医院心内科,南宁530021 [2]广西中医学院

出　　处：《中国医学文摘（老年医学）》2006年第4期203-205,共3页

摘　　要：目的:探讨老年冠心病患者血清尿酸水平与冠脉病变程度的相关性。方法:将498例行冠脉造影的老年患者分为冠心组(299例)和对照组(199例),分别测定血清尿酸、血糖、体重指数(BMI)、血脂水平。结果:老年冠心病患者血清尿酸水平明显高于对照组,有极显著性差异(P<0·01),相关分析提示血清尿酸水平与冠脉病变显著相关。结论:高尿酸血症可能是老年冠心病的危险因素之一。Objective To determine the relationship between severity degree of coronary lesions and hyperuricemia in elderly patients. Methods Serum concentration of uric acid was measured and other biochemical assessments such as serum level of Glucose, TG, TC, LDL - c, HDL- c were determined at a fasting state in 498 elderly patients who have undergone coronary angiography, and who classified into coronary heart disease （CHD） group （299） and normal control group （199）. The relationship between the severity degree of coronary lesions and serum level of uric acid was analyzed by using linear correlation and multiple stepwise regression. Results The serum level of uric acid in CHD group was significantly higher than that of normal coronary artery group （ P 〈0.01 ）. The linear correlation analysis showed serum level uric acid was significantly correlated with the severity degree of coronary lesions. Correlation analysis results showed that serum uric acid level was positively and significantly related to Glucose, TG, LDL-c and body mass index （ P 〈 0.05 or P 〈 0.01, respectively ）. The multiple stepwise regression showed serum level of uric acid was an independently related factor of coronary lesions. Conclusion Increased level of serum uric acid is a risk factor to CHD in the elderly.

关 键 词：高尿酸血症 冠状动脉疾病 危险因素 老年人 

分 类 号：R541.4[医药卫生—心血管疾病]