肝硬化患者Pd、QTd和JTd测定的临床意义  

Clinical significance of measuring P-wave dispersion,QT dispersion and JT dispersion of electrocardiogram in patients with liver cirrhosis

作　　者：田景波[1] 李京军[1] 王冰洁[1] 

机构地区：[1]青岛大学医学院第二附属医院感染科,266042

出　　处：《中国医师进修杂志》2006年第11期17-18,21,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的测定肝硬化患者心电图P波离散度(Pd)、QT离散度(QTd)及JT离散度(JTd)数值,探讨其临床意义。方法按Child分级标准将60例肝硬化患者分为A、B、C级三组,测量同步12导联心电图Pd、QTd和JTd数值变化以及与总胆红素、白蛋白的相关性,并与30例健康者(对照组)比较。结果肝硬化患者出现心电图改变者占61.7%,高于对照组(36.7%,P<0.05);Pd、QTd和JTd数值高于对照组(P<0.01);且三组间比较,差异有统计学意义(P<0.01);Pd、QTd和JTd与总胆红素呈正相关(P<0.01),与白蛋白呈负相关(P<0.01)。结论肝硬化患者存在着心电图的改变,Pd、QTd和JTd数值的变化可评价肝硬化的严重程度,并能了解预后及指导临床治疗。Objective To measure P - wave dispersion, QT dispersion and JT dispersion of electrocardiogram in patients with liver cirrhosis and study the clinical significance. Methods Sixty patients were divided into three groups of A, B and C by Child grade. Measured the changes of P - wave dispersion, QT dispersion and JT dispersion of deetrocardiogram, judged the correlation to serum total bilirubin and albumin, compared to the control group. Results The 61.7% patients changed in their electrocardiogram and were higher than the 36.7% of the control （ P 〈 0.05 ） ; The number of P - wave dispersion, QT dispersion and JT dispersion of electrocardiogram in patients were higher than those in control （ P 〈 0.01 ） ; the significant difference were existed in A, B and C group （ P 〈 0.01 ） ; there were the positive correlation to serum total bilirubin and the negative to albumin. Conclusions The changes of electrocardiogram are existed in patients with liver cirrhosis. The number of P - wave dispersion, QT dispersion and JT dispersion of electrocardiogram evaluate the degree of liver cirrhosis, and can judge the prognosis and guided the clinical treatment.

关 键 词：肝硬化 P波离散度 QT离散度 JT离散度 临床意义 

分 类 号：R575.2[医药卫生—消化系统]