肺瘤平Ⅱ号改善肺癌患者生存质量临床研究  

Clinical Study of Feiliuping Ⅱ on Quality of Life of Lung Cancer Patients

作　　者：冯利[1] 花宝金[2] 朴炳奎[2] 

机构地区：[1]中国中医科学院望京医院肿瘤科,北京100102 [2]中国中医科学院广安门医院肿瘤科,北京100053

出　　处：《中国中医药信息杂志》2006年第12期12-13,共2页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：中国中医科学院创新项目(CX-00-06);首都医学发展基金资助课题(首都ZD199902)

摘　　要：目的分析中药制剂肺瘤平Ⅱ号临床疗效及在改善肺癌患者生存质量方面的作用。方法将一般情况基本相同的60例中晚期非小细胞肺癌患者,随机分为化疗组30例,肺瘤平Ⅱ号加化疗组(中西医结合组)30例。中西医结合组在化疗的基础上给予肺瘤平Ⅱ号,20g/次,3次/d,口服,3个月为1个疗程。从临床疗效、证候改变以及生存质量等方面,对2组治疗结果进行评价。结果中西医结合组的病灶稳定率极显著高于单纯化疗组(P<0.01),显著改善了气阴两虚、血瘀证候表现,Karnofsky评分稳定提高率及体重稳定提高率也高于单纯化疗组。结论加服肺瘤平Ⅱ号对生存质量的改善优于单纯化疗组。Objective To study the clinical effect and influence of Feiliuping Ⅱ on the quality of life quality of lung cancer patients. Methods 60 patients of later stage of lung cancer with definite diagnosis and stages in pathology were chosen, who had approximate condition. Among them, 30 cases were in Chemotherapy- only group, and 30 cases were in Feiliuping Ⅱ ＋Chemotherapy group. Chemotherapy was the treatment in Chemotherapy-only group. Besides chemotherapy, Feiliuping Ⅱ was taken orally, 20 g tid poin Feiliuping Ⅱ ＋Chemotherapy group. Three months were a period of treatment. To evaluating effect of two groups from clinical curative effect, symptoms changes, and quality of life. Results After treatment, stable rate of focus were notably higher in Feiliuping Ⅱ ＋Chemotherapy group than that in Chemotherapy-only group （P〈0.01）, and symptoms of deficiency syndrome of both qi and yin along with blood stasis were notably improved in Feiliuping Ⅱ＋Chemotherapy group, whose stabilization and increasing rate of both Karnofsky and body weight were higher than those of Chemotherapy-only group too Conclusin In improving the quality of life, Feiliuping Ⅱ accompanied with chemotherapy was better than chemotherapy only.

关 键 词：肺瘤平Ⅱ号 非小细胞肺癌 生存质量 临床研究 

分 类 号：R734.2[医药卫生—肿瘤]