原发性开角型青光眼眼动脉、视网膜中央动脉血流动力学及与荧光血管造影的关系  

Hemodynamics of ocular artery and retinal central artery and its correlation with retinal f luoresceln angiography in primary open-angle glaucoma

作　　者：刘杏 周文炳 叶天才 葛坚 蔡小于 肖敏[2] 

机构地区：[1]广州中山眼科中心眼科医院,广州先烈南路54号510060 [2]广东省人民医院

出　　处：《眼科》1996年第4期195-198,共4页Ophthalmology in China

摘　　要：用彩色多普勒成像技术(CDI)分别检测了正常人和原发性开角型青光眼(POAG)患者102只眼的眼动脉(OA)和视网膜中央动脉(CRA)的血流动力学,结果表明POAG患者OA和CRA的收缩期最大血流速度、舒张末期血流速度和平均血流速度均比正常人减少。而阻力指数比正常人增高。线性回归分析表明POAG患者OA和CRA舒张末期血流速度之间存在正相关关系。多元回归分析显示POAG患者CRA收缩期最大血流速度与荧光血管造影之臂-视网膜动脉充盈时间呈负相关关系。表明POAG患者血流动力学呈异常改变并与视盘血液供应有密切关系。The hemodynamics of ocular artery (OA) and central retinal artery(CRA)in normal persons and patients (102 eyes, respectively)with primary open-angle glaucoma (POAG) were studied with color Doppler image technique. The results showed that average values of peak systolic flow velocity (Vmax), the end-diastolic flow velocity (Vmin) and the mean flow velocity (Vmeau)for the OA and CRA in glau-comatous patients we^e much lower than that in normal persons. But the mean resistance index (RI) was higher than that in normal persons. The linear regression analysis presented that there was a positive correlation of Vmin between the OA and CRA (r = 0.3278, p<0.001) in glaucomatous patients. Multiple regression analysis showed that there was a negative correlation between the Vmax of CRA and the arm to retinal arterial 'filling time of fluorescein angiography in patients with POAG. We propose that abnormal hemodynamics in glaucomatous. patients can affect the Mood supply to the optic disc and cause the damage of visual function.

关 键 词：开角型 青光眼 眼动脉 视网膜动脉 血流动力学 

分 类 号：R775.202[医药卫生—眼科]