老年性黄斑变性光学相干断层扫描观察  

Characteristics of age-related macular degeneration optical coherence tomography

作　　者：陈青山[1] 曾键[1] 余宝花[1] 李志[1] 谢秀英[1] 古洵清[1] 

机构地区：[1]暨南大学医学院深圳眼科中心,深圳市眼科医院,深圳518001

出　　处：《中国实用眼科杂志》2006年第11期1170-1173,共4页Chinese Journal of Practical Ophthalmology

摘　　要：目的观察萎缩型,渗出型老年黄斑变性(Age-relatedmaculardegenerationAMD)患者的光学相干断层扫描图像特征。比较光学相干断层扫描(OpticalCoherenceTomographyOCT)和荧光血管造影(FluoresceinangiographyFFA)的特点,对脉络膜新生血管(ChoroidalneovascularizationCNV)进行OCT分型。方法经FFA确诊的AMD57例76只[进行OCT检查。结果AMD患者色素上皮萎缩,软性玻璃膜疣,神经上皮和色素上皮脱离具有特有的OCT特征,OCT图像中视网膜神经上皮增厚、隆起反映视网膜下,视网膜层间积液。神经上皮或色素上皮(Retinalpigmentepithelium,RPE)隆起,其下低反射区反映神经上皮或RPE层脱离。CNV的OCT图像分为边界清晰的CNV,边界模糊的CNV,纤维血管性RPE脱离。FFA中的典型性CNV相当于OCT图像中边界清晰CNV,隐匿性CNV相当于OCT图像中边界模糊CNV和纤维血管性RPE脱离。结论OCT能特征性显示AMD中视网膜神经上皮隆起,视网膜层间积液,出血,神经上皮和RPE的脱离,且显示不同类型CNV的OCT特征。Objective To verify the characteristics of Ocular coherence tomography （OCT） in exudative and non-exudative age-related macular degeneration （AMD）. Methods 57 cases（76 eyes） with AMD diagnosed by FFA were performed OCT. Results The characteristics of the OCT images with retinal pigment epithelium （RPE） atrophy, soft drusen and retina or RPE detachment in patients were found, the OCT images of thick or elevated retina revealed sub-retinal or inter retinal fluids accumulation, the hyporeflectivity area under retina or RPE corresponded to retina or RPE detachment. The OCT images showed three types CNV： well-defined CNV, bad-defined CNV and fibrovascular pigment epithelium detachment.（PED） The classic CNV on FFA corresponded to well-defined CNV on OCT, the occult CNV on FFA corresponded to baddefined CNV or fibrovascular PED on OCT. Conclusion OCT could show retinal elevation, interretinal fluids accumulation, hemorrhage, retina or RPE detachment ,also showed the changes of CNV.

关 键 词：黄斑变性 光学相干断层照相 脉络膜新生血管 

分 类 号：R774.5[医药卫生—眼科]