依托咪酯用于无抽搐电休克治疗精神病287例的临床观察  

Clinical observation of etomidate in the application of MECT in 287 psychosis patients

作　　者：赵卫兵[1] 

机构地区：[1]淮安市第三人民医院麻醉科,江苏淮安223001

出　　处：《临床和实验医学杂志》2006年第12期1937-1938,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的探讨现代无抽搐电休克(MECT)治疗精神病的麻醉药物及监测选则。方法采用回顾性调查的方法,对我院2004年9月至2006年9月期间,接受治疗的287例精神病患者2181例次的临床资料进行归纳、整理、总结。结果2181例次MECT治疗未出现医疗意外和并发症;依托咪酯与异丙酚应用于无抽(搐电)休克治疗时,两者相比无太大差别。电刺激后两组心率和血压均明显升高,乙组变化较甲组大,但两组相比无特异性,入睡与清醒的时间相近,而且依托咪酯更易出现可供监测的麻醉慢波。结论依托咪酯作为价格相对较低的全麻醉药,可完全替代异丙酚应用于无抽(搐电)休克治疗,且效果更佳。Objective The purpose of this study is to approach the suitable drug of general anesthesia for the treatment and monitorring of electric shock in psychosis patients. Methods Clinical data was collected from 287 patients with psychosis （2181 person - time） who were treated in the hospital from September 2004 to June 2006. Results Medical emergency and complication did not occur in patients received maintenance electroconvulsive therapy （MECT）. There were no obvious differences in the effect of etomldate and propofol on MECT. Both HR and BP increased after electric stimulation, but no significant differences were found between the two treatment groups. The time to fall asleep and regain consciousness was also close to each other in the two groups. The fact that more anaesthesia slow waves appeared in etomidate group indicated that etomidate was better drug for monitoring. Conclusion As a low price drug for general anesthesia, etomidate may completely substitute propofol for MECT.

关 键 词：无抽搐电休克 依托咪酯 监测 

分 类 号：R749.05[医药卫生—神经病学与精神病学]