HIV感染者和AIDS患者口腔非特异性溃疡  

Oral ulceration not otherwise specified in HIV-infected and AIDS individuals

作　　者：熊卉[1] 陈建钢[1] 桂希恩[2] 

机构地区：[1]武汉大学中南医院口腔科,湖北武汉430071 [2]武汉大学中南医院传染科

出　　处：《口腔医学研究》2006年第6期629-631,共3页Journal of Oral Science Research

基　　金：湖北省自然科学基金资助项目(编号:2004ABA168)

摘　　要：目的：口腔非特异性（NOS）溃疡是一类与HIV感染有关的口腔病变，其临床表现不同于常见口腔溃疡。通过对NOS口腔溃疡临床特征的分析，为临床医师提供鉴别诊断。方法：回顾性分析72例HIV／AIDS患者，NOS口腔溃疡有3例，探讨其临床特征并与复发性阿弗他溃疡、单纯疱疹性口炎进行比较，探讨其发病机制。结果：NOS口腔溃疡的好发部位为软腭、口咽及舌腭弓处，常为1～2个，病程较长，cD。＋细胞明显减少，多伴发白色念珠菌感染。结论：NOS口腔溃疡的发病部位、病程与预后较为特殊，与AIDS的病程进展有一定的联系。Objective： Ulceration NOS （not otherwise specified ） was a sort of oral lesions associated with HIV infection which had special clinical manifestations. The features of ulceration NOS were described and the differential diagnosis were provided for the clinican. Methods： A toatal of 72 HIV - infected/AIDS individuals were examined for oral ulcers. Ulceration NOS was found in 3 patients, of which the clinical manifestations were described and compared with recurrent aphthous ulcers and herpetic stomatitis. The pathogenesis of ulceration NOS was discussed. Results： Ulceration NOS lesions with a predilection for the soft palate, the oropharynx and the anterior palatine were observed. The clinical features were ulceration number （one or two）, duration（ more than 3 months）, and CD4＋ T cell count （reduced obviously）. Two of three patients had concomitant candida albicans infection. Conclusion： Ulceration NOS was a special sort of ulceration in the sites, the course of disease and the prognosis, which had some connection with the course of AIDS.

关 键 词：艾滋病 HIV 口腔非特异性(NOS)溃疡 

分 类 号：R781.5[医药卫生—口腔医学]