肝胆管结石合并胆管癌的临床分析  

Clinical Analysis to hepatolithiasis combined with cholangiocarcinoma

作　　者：张龙轩[1] 徐祗永[2] 王军业[3] 刘瑞林 戴淑琴[4] 

机构地区：[1]临沂市人民医院普通外科,山东临沂276005 [2]临沭县中医院普通外科,山东临沭276700 [3]中山大学肿瘤防治中心华南肿瘤学国家重点实验室胸科,广东广州510060 [4]中山大学肿瘤防治中心华南肿瘤学国家重点实验室检验科,广东广州510060

出　　处：《中华肿瘤防治杂志》2006年第20期1588-1590,共3页Chinese Journal of Cancer Prevention and Treatment

摘　　要：为了探讨肝胆管结石合并胆管癌的诊治经验，总结1998年6月～2005年6月我院收治的22例肝胆管结石合并胆管癌患者的临床资料。结果：术前超声检查诊断正确率50％（11／22），CT检查正确率66．6％（12／18）。根治性手术13例，姑息性手术7例，单纯活栓2例。随访22例，根治组平均存活24个月，姑息组平均存活11个月。单纯活栓者术后6个月内均死亡。初步研究结果提示，胆管癌的发生与肝胆管结石有关；伴有结石的胆管癌疗效较差，应重视胆管结石的早期根治性治疗，以防止胆管癌的发生；姑息性手术可提高生活质量。In order to The discuss diagnosis and treatment experience of hepatolithiasis combined with cholangiocarcinorna, 22 cases of hepatolithiasis combined with cholangiocarcinorna from June 1998 to June 2005 in our hospital were investigated. Results： the correct rate of preoperative ultrasonic diagnosis was 50% （11/22）, and that of CT diagnosis was 66.6 （12//18）. Thirteen cases were radically resected, 7 cases treated by palliative therapy, and 2 cases examined only with biopsy, and all the cases were followed up. The average survival time of the patients performed radical resection was 24 months, and that of the patients performed palliative therapy was 11 months, and all the cases examined only with biopsy died in 6 months after the biopsy. In conclusion, cholangiocarcinoma may be is elated to hepatolithiasis. The therapeutic effect of cholangiocarcinoma combined with hepatolithiasis was poor. Early radical therapy for hepatolithasis plays an important role in preventing cholangiocarcinoma occurrence. Drainage therapy for cholangiocarcinoma may improve the quality of life.

关 键 词：胆管上皮癌/并发症 胆管肿瘤/并发症 胆结石/并发症 

分 类 号：R735.8[医药卫生—肿瘤]