冠心病患者的抑郁症状与C-反应蛋白的相关性研究  

The Relationship Between C-reactive Protein and Depressive Symptoms in Patients with Coronary Heart Disease

作　　者：方建群[1] 白秀琴[2] 

机构地区：[1]宁夏医学院心理学教研室及附属医院综合科,银川750004 [2]宁夏医学院附属医院综合科,银川750004

出　　处：《宁夏医学院学报》2006年第6期490-491,496,共3页Journal of Ningxia Medical College

摘　　要：目的探讨冠心病患者的抑郁症状与C-反应蛋白(CRP)水平的关系。方法选择冠心病患者62例(实验组),其中急性冠脉综合征27例,稳定性心绞痛35例,正常人30例(对照组);分别测定其血浆CRP浓度,并采用Zung氏抑郁自评量表(SDS)评定抑郁症状。结果冠心病患者抑郁的躯体性障碍和抑郁的心理性障碍评分、血浆CRP水平明显高于正常人(P<0.05),急性冠脉综合征者的CRP水平高于稳定性心绞痛者;冠心病患者的CRP与抑郁的躯体性障碍和心理性障碍显著相关。结论冠心病患者的血浆CRP水平与抑郁的躯体性障碍和心理性障碍相关,与抑郁心境无关。Objective To investigate the relationship between C-reactive pmtein（CRP） and depressive symptoms in patients with coronary heart disease （CHD）. Methods 62 patients with CHD, including 27 acute coronary syndrome and 35 stable angina pectoris, and 30 normal controls were assessed with self-rating depression scale （SDS）. The serum CRP levels were measured. Results CRP levels were correlated with the psychological disorders and the somatic symptoms of depression in patients with CHD. Conclusion CRP was associated with the somatic symptoms and the psychological disorders of depression in patients with CHD. The association between CRP and depressive mood was not found.

关 键 词：冠心病 C反应蛋白 稳定性心绞痛 

分 类 号：R749.2[医药卫生—神经病学与精神病学]