5种新癫综合征的临床及流行病学特征  

Clinical and epidemiological features of the five kinds of new epileptic syndrome

作　　者：王学峰[1] 朱曦[1] 沈鼎烈[1] 关立峰[1] 晏勇[1] 

机构地区：[1]重庆医科大学附属第一医院神经内科重庆市神经病学重点实验室,400016

出　　处：《中华医学杂志》2006年第47期3319-3323,共5页National Medical Journal of China

摘　　要：目的了解5种新的癫综合征在癫人群中的分布及临床特征。方法用电脑查询和手工检索的方法,对近30年来在重庆医科大学附属第一医院癫中心就诊,并有完整病历记录的5300例患者进行新癫综合征的调查。结果本次研究实际完成调查数为4894例。其中111例有明确癫家族史,包括2例家族性颞叶癫,1例具不同病灶的家族性部分性癫和3例全面性癫伴热性惊厥叠加综合征,另有14例符合颞叶内侧癫和5例符合惊吓性癫的临床特征。没有发现偏侧惊厥-偏瘫癫综合征和常染色体显性遗传夜间额叶癫综合征的患者。结论国际抗癫联盟新提出的癫综合征在国内癫人群中也存在,了解这些综合征的临床特点有助于更好的诊治此类疾病。Objective To investigate the clinical and epidemiological feature of the five kinds of new epileptically syndrome. Method A retrospective study was conducted, by computer inquiry and manual retrieval, on 5300 patients with complete history records who had been followed up regularly in the epilepsy center of the First Affiliated Hospital of Chongqing University in the past 20 years to discover the cases that could be diagnosed as with the five kinds of new epileptic syndromes. Results Survey was finished in 4894 of the 5300 patients. Two cases of familial temporal lobe epilepsy, one case of familial partial epilepsy with variable foci, fourteen cases with mesial temporal epilepsy, and five cases with startle-provoked epileptic were discovered. Conclusion Patients with the five kinds of new epileptic syndrome have been discovered in China too. It is beneficial to study the clinical and epidemiological features of those new epileptic syndromes.

关 键 词：癫痫综合征 遗传 癫痫 

分 类 号：R742.1[医药卫生—神经病学与精神病学]