正电子发射型计算机断层扫描/计算机体层扫描对原发性肺癌的诊断价值  

Use of positron emission tomography/computer tomography scanning in the diagnosis of primary lung cancer

作　　者：常林凤[1] 卢光明[2] 朱虹[1] 王中秋[2] 吴江[1] 胡裕效[1] 秦利萍[1] 王玲[1] 

机构地区：[1]南方医科大学南京临床医学院(南京军区南京总医院)核医学科,江苏南京21000 [2]南方医科大学南京临床医学院(南京军区南京总医院)医学影像科,江苏南京21000

出　　处：《医学研究生学报》2006年第12期1081-1084,共4页Journal of Medical Postgraduates

基　　金：国家973计划基金资助项目(批准号:2006CB705707)

摘　　要：目的:探讨正电子发射型计算机断层扫描仪/计算机体层扫描(PET/CT)早期及延迟显像对原发性肺癌的诊断价值。方法:43例经病理证实的原发性肺癌患者,均行PET/CT早期及延迟显像,观察瘤体PET图像上标准摄取值以及延迟显像后标准摄取值变化,分析肺部病变CT形态、密度、边界、毛刺等征象,分别统计PET、CT和PET/CT对原发性肺癌诊断的准确率和假阴性率。结果:40例患者PET图像表现为标准摄取值(SUV)>2.5,3例SUV<2.5,诊断的准确率和假阴性率分别为93.0%和7.0%;24例延迟显像上升>10%,诊断的准确率和假阴性率分别为68.5%和31.5%;36例CT图像表现为边缘不规则,分叶、毛刺,诊断的准确率和假阴性率分别为83.7%和16.3%;PET/CT显示37例为肺癌,6例可疑肺癌,诊断的准确率和假阴性率分别为86.0%和0。结论:行PET/CT早期显像对原发性肺癌诊断有重要价值,但存在假阴性,而延迟显像有一定价值。Objective ：The purpose of this study was to evaluated the accuracy of positron emission tomography （PET）/computer tomography （CT） imaging in the diagnosis of primary lung cancer. Methods. Forty-three cases of pathologically proved primary lung cancer underwent early and dual time point Fluorodeoxyglucose PET/CT scanning. The standardized uptake values （SUV） were calculated for both time points. The rates of accuracy and false negative of PET, CT and PET/CT were calculated respectively. Results：Among the 43 cases of primary lung cancer, 40 cases showed SUV 〉2.5,and the other 3 cases showed SUV 〈 2.5. The rates of accuracy and false negative were 93.0 % and 7.0 %, respectively. Dual time point scanning with a threshold value of 10 % increase resulted in the rates of accuracy and false negative as 68.5 % and 31.5 %, respectively. The other rates of accuracy and false negative were 83.7 % and 16.3 % for CT, 86.0% and 0% for PET/CT, respectively. Conclusion ：PET/CT scanning is valuable for the diagnosis of primary lung cancer. Dual time point PET/CT scanning may be helpful in differential diagnosis.

关 键 词：原发性肺癌 正电子发射型计算机断层扫描仪/计算机体层扫描 氟去氧葡萄糖 

分 类 号：R734.2[医药卫生—肿瘤]