米安色林与博乐欣治疗抑郁症疗效研究  

Study of Miqnserin and Vanlafaxine in the treatment of depression

作　　者：刘增龙[1] 韩建生[1] 颜敏[1] 成玉敏[1] 周会爽[1] 赵明坤[1] 

机构地区：[1]河北省第六人民医院,河北保定071000

出　　处：《河北职工医学院学报》2006年第4期9-11,共3页Journal of Hebei Medical College for Continuing Education

摘　　要：目的比较米安色林和博乐欣治疗抑郁症的疗效和不良反应。方法以CCMD-3作为诊断标准,采用HAMD、TESS量表及其临床疗效评定标准分别评定疗效和副反应。结果米安色林和博乐欣的疗效相近,米安色林的临床治愈率和总有效率分别为53％和84％,博乐欣的临床治愈率和总有效率分别为60％和90％。结论两者临床疗效无显著差异,但博乐欣起效快,副反应小,米安色林服药方便。Objective To compare the efficacy and the side effects of Mianserin and Vanlafaxinine in the treatment of depression. Methods According to the CCMD -3, the efficacy and its side effects were evaluated with HAMD,TESS,CGI_SI. Results Both drugs had similar efficacy in the treatment of depression：the cured rate and the clinical improvements rate of Mianserin were 53 % and 84% respectively wthe cured rate and the clinical improvements rate of Vanlafaxine were 60% and 90% respectively . Conclution The results show that the efficacy of Mianserin is similar with that of Vanlafaxine, Vanlafaxine is an effective and safe antidepressant, but Mianserin is convenient.

关 键 词：抑郁症 米安色林 博乐欣 

分 类 号：R749.4[医药卫生—神经病学与精神病学]