急性高血压性脑出血抗自由基治疗临床研究  

Clinical study of Free Radical Scavenger on The Treatment of Acute Hypertensive Cerebral Hemorrhage

作　　者：丁朝兵[1] 陈东[1] 周易谦[1] 唐金荣[2] 丁新生[2] 侯熙德[2] 

机构地区：[1]江苏省大丰市人民医院神经内科,224100 [2]南京医科大学第一附属医院神经内科

出　　处：《脑与神经疾病杂志》2006年第6期427-428,共2页Journal of Brain and Nervous Diseases

摘　　要：目的：探讨急性高血压性脑出血抗自由基治疗，评定其疗效。方法：将58例急性高血压性脑出血患者随机均分为治疗组和对照组，治疗组在常规治疗的基础上加用依达拉奉，对照组仅采用常规治疗。两组于治疗前和治疗后14天分别进行神经功能缺失评分和疗效评定。结果：治疗组总有效率、病死率、神经功能缺失评分（ESS）、生活能力（ADL）与对照纽比较有显著差异（P〈0．05～0．01）。结论：依达拉奉可促进急性高血压性脑出血患者神经功能康复。Objective：To evaluate the efficacy of free radical scavenger on the treatment of acute cerebral hemorrhage and to evaluate its therapeutic effect. Methods： 58 patients were divided into treatment group and control group randomly. Necurological functional deficit scores were utilized for assessment before given treatment, on the 14th day after treatment, the patient was assessed again and the efficacy was recorded. Results： The total effective rate, the mortality rate, the Necurological functional deficit scores（ESS） and ability of daily life （ADL）of the treatment group were significantly difference than the control group （P〈0.05-0.01）,Conclusions： Edaravone can accelerate the recovery of neural function after acute cerebral Hemorrhage.

关 键 词：高血压性脑出血 抗自由基 临床疗效 

分 类 号：R743.34[医药卫生—神经病学与精神病学]