肝脏动静脉渡越时间对原发性肝癌肝脏血流动力学的研究  

Hepatic Arteriovenous Transit Time Effect on Hepatic Homodynamic Changes in HCC Patients Using Contrast-enhanced Ultrasonography

作　　者：李凡[1] 杜联芳[1] 

机构地区：[1]上海交通大学附属第一人民医院超声科,上海市200080

出　　处：《中国超声医学杂志》2007年第1期40-42,共3页Chinese Journal of Ultrasound in Medicine

基　　金：上海市卫生局资助项目(No.044010)

摘　　要：目的研究肝脏动静脉渡越时间(hepaticarteriovenoustransittime,HAVTT)在原发性肝细胞肝癌(hepaticcellcarcinoma,HCC)患者中的改变及其对肝脏血流动力学的影响。方法对147例肝脏(非肝硬化HCC组10例,肝硬化HCC组51例,肝硬化组52例,正常对照组34例)行超声造影检查,测量HAVTT。结果正常组与非肝硬化HCC组间HAVTT无明显差异(P>0.05)。肝硬化HCC组HAVTT较非肝硬化HCC组及单纯肝硬化组明显缩短(P<0.05),且在ChildA、C级HCC组间差异显著(P<0.05)。结论肝硬化合并HCC患者HAVTT明显缩短,ChildC级HCC患者的HAVTT明显短于ChildA级HCC。Objective To study the influence of hepatic arteriovenous transit time （HAVTT） changes on hepatic hemodynamics in patients with hepatic cell carcinoma （HCC） . Methods One hundred and fourty seven patients including 10 non-cirrhotic HCC, 51 cirrhotic HCC, 52 cirrhosis patients and 34 healthy adults underwent contrastenhanced ultrasonography. HAVTT were analyzed after injection of SonoVue into an arm vein. Results There was no significant difference between healthy adults and non-cirrhotic HCC patients （P〉 0. 05）. HAVTT was significantly shorter in cirrhostic HCC group than in non-cirrhostic HCC and cirrhosis group （P〈0.05）, and HAVTT had also significant difference between Child A HCC and Child C HCC group （P 〈 0.05） . Conclusions HAVTT was significantly shorter in cirrhosis patients with HCC, especially shorter in Child C than in Child A patients.

关 键 词：超声检查 对比造影剂 原发性肝细胞肝癌 时间 

分 类 号：R735.7[医药卫生—肿瘤]