Capillary electrophoresis-chemiluminecence detection of levodopa and benserazide in Medopar tablet  

作　　者：Wei Wei He Xing Wang Zhou Jian Quan Lu 

机构地区：[1]College of Chemistry, Central China Normal University, Wuhan 430079, China [2]Hubei Key Laboratory of Bioanalytical Technology, Hubei Normal University, Huangshi 435002, China

出　　处：《Chinese Chemical Letters》2007年第1期91-93,共3页中国化学快报（英文版）

基　　金：This work was supported by Science Foundation of the National Education Ministry(No.206096);Education Department of Hubei Province(No.Z200522002),

摘　　要：A novel method for the simultaneous determination of benserazide and levodopa using capillary electrophoresis （CE）- chemiluminescence （CL） has been developed. Under the optimal conditions, the detection limits （S/N = 3） were 1.85 μg/mL for benserazide and 0.12 μg/mL for levodopa. This method was successfully applied to the determination of benserazide and levodopa in Medopar tablet, the results showed that the detected values are in accordance with those by official methods.A novel method for the simultaneous determination of benserazide and levodopa using capillary electrophoresis （CE）- chemiluminescence （CL） has been developed. Under the optimal conditions, the detection limits （S/N = 3） were 1.85 μg/mL for benserazide and 0.12 μg/mL for levodopa. This method was successfully applied to the determination of benserazide and levodopa in Medopar tablet, the results showed that the detected values are in accordance with those by official methods.

关 键 词：BENSERAZIDE LEVODOPA Capillary electrophoresis CHEMILUMINESCENCE 

分 类 号：R927.2[医药卫生—药学] R971.5