高检测灵敏度的DNA生物传感器  

High Sensitive DNA Biosensors

作　　者：房少华[1] 程秀兰[1] 

机构地区：[1]上海交通大学微电子学院,上海200030

出　　处：《微纳电子技术》2007年第1期34-38,42,共6页Micronanoelectronic Technology

基　　金：上海交通大学青年教师校内科研启动基金;上海市科委重大项目资助(03DZ14025)

摘　　要：基于磁珠带标记DNA电化学传感器、磁珠标记的GMR(TMR)DNA生物传感器和纳米线场效应DNA生物传感器都具有高检测灵敏度的特点,是极具发展前途的研究方向。主要介绍了以上三种高检测灵敏度DNA生物传感器的基本检测原理,并对比分析了这三种传感器的优缺点。Recently years some new schemes about DNA biosensor were presented. Among them, bead-based and labeled electrochemical DNA biosensor, bead-labeled GMR （TMR） DNA biosensor and nanowire field-effect DNA biosensor were of higher sensitivity. The principles of the three kinds of novel DNA biosensors were introduced, and their features and challenges were reviewed.

关 键 词：DNA生物传感器 磁珠 巨磁效应 隧道磁电阻效应 纳米线 

分 类 号：Q523[生物学—生物化学]