早期心理干预对精神分裂症后抑郁的影响  

Effect of Early Psychotherapy on Post-schizophrenia Depression

作　　者：李桂林[1] 宗丽春[1] 田淑英[2] 张玉琦[1] 

机构地区：[1]南京医科大学附属无锡精神卫生中心,中国214151 [2]山东省安康医院

出　　处：《中国健康心理学杂志》2007年第1期24-26,共3页China Journal of Health Psychology

摘　　要：目的探讨早期心理干顶对预防精神分裂症后抑郁的影响。方法采用病例—对照的研究方法,将568例精神分裂症病人随机分成心理干预组和对照组,每组各284例。对照组给予抗精神病药物,心理干预组在给予抗精神病药物加心理干预。两组患者分别于治疗前和治疗8周末给予PANSS量表和汉密顿抑郁量表评定。结果治疗8周后,心理干预组显效195例(68.7%)、有效236例(92.61%),对照组显效172例(60.6%)、有效248例(87.3%),两组显效率及有效率差异均有统计学意义(P均<0.05)。心理干预组产生中、重度抑郁症状者共56例,对照组产生中、重度抑郁症状者共86例,差异有统计学意义(P<0.05)。结论早期心理干预能够提高治疗效果,减少精神分裂症后抑郁症状的发生。Objective To study the effect of early psychotherapy on post-schizophrenia depression. Methods 568 patients were randomly divided into research （antagonize psychopathy drug with supportive psychotherapy, n-284） and control （antagonize psyehopathy drug, n^281） groups. Effieaeies and side effects were assessed with Hamilton Depresion Rating Scale （HDRS） and the Positive and Negative Syndrome Scale （PANSS） before treatment and the ends of 8 week of the treatment respectively. Results The significant efficacy rates of research was 68.70% and the efficacy rate was 92.6% after 8 weeks while that was 60. 6% and 87.3% in control group. There was significant difference between the two groups （P〈0. 05）. The research group has depression 56, and control group 86. There was significant difference in generant rate between the two groups （P〈0. 05）. Conclusion It was capable enhance of curative effect, and play down generant rate of postschizophrenia depression that the early supportive psychotherapy prevent.

关 键 词：心理干预 精神分裂症后抑郁 预防 

分 类 号：R749.3[医药卫生—神经病学与精神病学]