垂体瘤X刀单次与多次治疗效果比较  

Brain complications and therapeutic effects of pituitary adenomas treated with X-knife using SRS or SRT methods

作　　者：郭化东[1] 姜秀玲[2] 王滨[1] 王俊英[1] 

机构地区：[1]泰山医学院附属医院肿瘤放疗中心,山东泰安271000 [2]枣庄市立医院,山东枣庄277100

出　　处：《实用医药杂志》2007年第1期13-14,共2页Practical Journal of Medicine & Pharmacy

摘　　要：目的探讨垂体瘤行单次治疗(SRS)与分次治疗(SRT)后对并发症发生率的影响。方法对近6年行X刀治疗的87例垂体瘤患者的资料作回顾性分析,分为SRS与SRT两组,比较两者对正常组织的生物学效应剂量与靶区体积。结果在相同的生物学周边参考剂量及体积下,0.5年内SRS并发症为9/28,SRT无并发症,SRS发生率高于SRT,SRT治疗效果优于SRS。结论SRT是降低颅内并发症的可靠的方法,能提高垂体瘤治疗的效果。Objective To study the incidence rate of brain complication after pituitary adenoma had been treated with X-knife.Methods There were 87 cases who had pituitary adenomas and lived more than 6 months after treatment using the methods of fractioned stereotactic radiotherapy （SRT） or single session （SRS）.Their effective biological reference doses and target volumes between SRT and SRS were compared.Result 9 cases had SRS complications in 28 cases, while there was not complications in 59 cases treated by SRT with in 6 months in common （P） effective biological reference doses and ）reating volumes.Conclusion SRT is an effective methods to reduce brain complications treated with X-knife and enhance the effects of treatment.

关 键 词：垂体瘤 立体放射治疗 并发症 

分 类 号：R730.55[医药卫生—肿瘤]