血管内支架成形术治疗症状性大脑中动脉狭窄  

Endovascular stenting for symptomatic stenosis of middle cerebral arterial

作　　者：熊家锐 王本瀚 王庆宣 张月高 郭效东 张长远 

机构地区：[1]153医院神经外科,河南郑州450042

出　　处：《实用医药杂志》2007年第1期23-25,共3页Practical Journal of Medicine & Pharmacy

摘　　要：目的初步总结分析血管内支架成形术治疗症状性大脑中动脉狭窄的疗效与技术经验。方法对25例反复短暂性脑缺血发作(TIA)、药物治疗无效的大脑中动脉狭窄患者,行血管内支架成形术,术后脑血管造影及TCD随访。结果25例患者血管狭窄部位均位于大脑中动脉M1段,术前狭窄为(88.2±4.4)%,术后即刻血管造影狭窄下降为(12.3±4.5)%。临床随访无TIA再发作,DSA随访无血管再狭窄,TCD检查脑血流明显改善。结论血管内支架成形术治疗大脑中动脉狭窄安全有效,但远期疗效还需进一步观察。Objective To evaluate the outcome of endovascular stenting for symptomatic stenosis of MCA, and to discuss our preliminary experience.Methods＇ Twenty five stenosis of MCA in twenty five patients , who had recurrent transient ischemic attacks （TIAs） resistant to medical therapy, underwent endovascular stent-assisted angioplasty. After stenting,the patients was administrated antiplatelet drug and followed up with DSA,TCD. Results The endovascular stent-assisted angioplasty was successful for all 25 stenoses .without complications related to the operation, the mean degree of stenosls reduced from （88.2±4.4）% to （12.3±4.5）%. No recurrent TIA and stroke was noted for all patients during clinical follow-up （5＇24months after stenting）.Follow-up angiogram in 21 patients revealed no restenosis, though 1 patient revealed mild endothelial hyperplasia.TCD suggested significant improvement of cerebral perfusion. Conclusion Endovascular stenting for symptomatic MCA stenosis is safe,reliable,and effectivc.lt is necessary for the long-term efficacy be further observed.

关 键 词：支架 脑缺血 狭窄 血管成形术 

分 类 号：R743.31[医药卫生—神经病学与精神病学] R815[医药卫生—临床医学]