急性脑血管病患者血清肿瘤坏死因子α的变化  

Changes of serum concentrations of tumor necrosis factor-α in patients with acute cerebrovascular diseases

作　　者：杨益阶[1] 唐尊立[1] 代红源[1] 高恩惠 

机构地区：[1]湖北医科大学附一医院神经科

出　　处：《中风与神经疾病杂志》1996年第5期273-274,共2页Journal of Apoplexy and Nervous Diseases

摘　　要：采用放射免疫法，检测了６２例脑梗塞和５３例脑出血急性期患者血清肿瘤坏死因子α（ＴＮＦ－α）的含量。结果发现，两患者组ＴＮＦ－α均明显高于对照组（Ｐ＜０．００１）。提示在脑梗塞和脑出血的发病过程中，都存在着ＴＮＦ－α介导的免疫反应。The serum concentrations tumor necrosis factor-α(TNF -α) were measured by radioimmunoassay in 62 patients with acute cerebral infarction(CI) and 53 cerebral hemorrhage (CH ) and results were compared with those in 20 healthy controls.The levels of TNF-α in CI and CH were significantly higher than those of the controls (P<0. 001 ) . The results suggested that an immunological response mediated by TNF-α is present in the pathogenesis of both CI and CH.

关 键 词：脑血管意外 肿瘤坏死因子 ACVD 

分 类 号：R743.3[医药卫生—神经病学与精神病学]