TECIA法体外药敏实验对实体瘤化疗个体化方案选择的意义  

Study on the chemosensitivity test with TECIA of solid tumor in vitro and the choice of individualized chemotherapy

作　　者：雷光焰 张曦 雷洁 

机构地区：[1]陕西省肿瘤医院,陕西西安710061 [2]南京先声医药有限公司,江苏南京210042

出　　处：《现代肿瘤医学》2007年第2期172-174,共3页Journal of Modern Oncology

摘　　要：目的：通过实体瘤体外药敏实验指导化疗方案选择，实现肿瘤化疗个体化。方法：采用TECIA法对56例肿瘤组织标本进行体外组织培养，并用常见十二种化疗药物进行药物敏感性试验，以试验结果与常用的经典化疗方案进行敏感符合性分析。结果：56份标本对常见化疗药高敏感占11．6％，中敏感46．0％；药敏结果与经典化疗方案符合率为50％～100％。结论：肿瘤药物敏感实验对指导患者的个体化治疗具有重要的价值。Objective： To study the effect of chemosensitivity test in vitro for solid tumor, nethosds： The sensitivity of 56 solid tumor samples forl2 commonly- used Antonio plastics was determined by TECIA method. Results： Some cases were low sensitive to classical chemotherapeutic regimen, or drug resistant. Conclusion： The in vitro chemosensitivity tests have important value to determine the individualized chemotherapy.

关 键 词：实体瘤 TECIA 药敏 

分 类 号：R730.53[医药卫生—肿瘤]