芬太尼缓释透皮贴剂治疗介入栓塞术后疼痛的疗效观察  

Clinical observation of abirritation and side-effect of transdermal fentanyl (TDF) in interventional embolization therapy

作　　者：朱旭[1] 杨仁杰[1] 陈辉[1] 张宏志[1] 

机构地区：[1]北京大学临床肿瘤学院,北京市肿瘤防治研究所,北京肿瘤医院,北京100036

出　　处：《现代肿瘤医学》2007年第2期261-262,共2页Journal of Modern Oncology

摘　　要：目的观察介入治疗栓塞术后芬太尼缓释透皮贴剂(transdermalfentanyl,TDF,多瑞吉)镇痛的效果及副作用。方法介入治疗栓塞术病人34例,于术后即刻给予吗啡10mg肌注及使用TDF,剂型25μg/h和50μg/h二种,术后观察镇痛效果及相关的副作用。结果绝大多数病人均获得满意的镇痛效果,以50μg/h较25μg/h为优,但恶心、呕吐、头晕发生率以50μg/h多见,全组无呼吸抑制。结论TDF可有效的用于介入栓塞术后的镇痛。Objective： To observe the abirritation and side effect of transdermal fentanyl （TDF） in interventional embolization therapy. Methods： 10mg morphine and 25 μg/h （or 50μg/h） fentanyl were immediately used in 34 patients who had underwent interventional embolization therapy, then the abirritation and side effect of transdermal fentanyl were obseved. Results： Most patients got satisfactory abirritation, the effect was better in 50μg/h group compared with 25μg/h group, but incidence of nausea, vomoting and dizzy were higher in 50μg/h group. No respiration inhibition were observed. Conclusion： TDF was an effective analgetic in interventional embolization therapy.

关 键 词：芬太尼缓释透皮贴剂 介入治疗栓塞术 术后镇痛 

分 类 号：R730[医药卫生—肿瘤]