斯普林治疗化疗所致骨髓抑制和改善生活质量的效果  

The effect of sipulin in improving marrow depress and sympton induced by chemotherapy

作　　者：高德荣[1] 温珍平[1] 王磊[1] 韩雅玲[1] 李红[1] 

机构地区：[1]内蒙古医学院附属人民医院肿瘤科,内蒙古呼和浩特010020

出　　处：《现代肿瘤医学》2007年第2期262-263,共2页Journal of Modern Oncology

摘　　要：目的：观察斯普林对恶性肿瘤患者化疗的辅助疗效。方法：化疗前2个周期不加斯普林，后3个-6个周期加斯普林，10ml／日，静脉点滴，每周期连用10天，从化疗第1日开始。所有患者加斯普林前后方案、剂量完全相同。结果：22例化疗患者加斯普林治疗前后外周血象及临床毒副反应有明显变化，加斯普林前WBC、PCT、HB发生Ⅰ度-Ⅲ度反应分别为72．7％、45．5％、31．7％，加斯普林后发生Ⅰ度-Ⅲ度反应分别为45．4％、40．9％、22．7％。加斯普林前神疲乏力、食欲不振、腹胀／便秘发生率为100％，加斯普林后症状好转56．2％，消失43．8％，有效率100％。结论：斯普林具有升高外周血象、改善生活质量、提高患者对化疗耐受性的作用。Objective： To observe the effect combined spulin with chemotherapy in the patients with malignant tumour. Methods：Twenty two advanced malighamt tumour patients tvedated with four or six cycles chemotherapy, every cycle was 21 days. After 1 and 2 cyles patients were given sipulin 10ml/d,lasted 10 days. Results： All patients who were given sipulin had obvious changes in blood routine and drug effects. Before use the sipulin, WBC, PCT, HB occur Ⅰ-Ⅲ actions,in 72.7% ,45.5% ,31.7% ,patients respectively, patients not given sipulin appeared frazzle, inappetence and constipation were 100% after chemotherapy. The effective rate of sipulin in the improving symptoms of patients was 100%. Conclusion： Sipulin can improve the blood routine, life quality and tolerance of the patients with chemotherapy.

关 键 词：恶性肿瘤 化疗 骨髓抑制 生活质量 斯普林 

分 类 号：R730.53[医药卫生—肿瘤]