互信息医学图像配准研究与局部极值的克服  

Research of medical image registration based on mutual information and overcome of local-maxima

作　　者：徐东[1] 李升辉[2] 

机构地区：[1]山东大学信息科学与工程学院,济南250100 [2]南京邮电大学信号与信息处理系,南京210003

出　　处：《计算机工程与应用》2007年第3期217-219,238,共4页Computer Engineering and Applications

摘　　要：研究了基于互信息的三维医学图像配准,并克服了的局部极值问题。改进了互信息和归一化互信息的公式,减小了计算量;对Powell算法的方向替换策略进行矫正,最大限度地保持原搜索方向;采用预设旋转量的方法有效解决了插值赝像局部极值问题。采用背景阈值策略,减小了互信息的计算区域,应用形态学方法,去除了PET图像的背景伪迹,使用了多分辨率策略,有效地提高了配准的速度。实验表明,用该改进的算法进行三维医学图像配准可以达到亚像素精度,且在速度上有了明显的提高。3-D medical image registration based on mutual information is researched in this paper and local maxima are overcome.The MI＇s formula is improved to reduce computation cost,.and the replacement of PoweU＇s search direction is also rectified to reserve the search direction and escape local maximum,initial set of rotation can avoid local maximum induced by interpolation anti-facts.Threshold is set to reduce iteration region ,morphology method is used to reduce noise of PET image ,multi-resolution method is adopted to accelerate the registration.The results show that the modified MI measure can reach sub-voxel precision,and the registration time is reduced obvlously,is a robust and precise method.

关 键 词：医学图像配准 归一化互信息 POWELL算法 插值赝像 形态学 

分 类 号：TP391[自动化与计算机技术—计算机应用技术]