Bel亚型鉴定及家系调查  

Identification and Domestic Investigation of Bel Subtypes

作　　者：别立莉 杨瑞云 张伯伟 郭如华 

机构地区：[1]河南省血液中心,郑州450012

出　　处：《中国实验血液学杂志》2007年第1期188-190,共3页Journal of Experimental Hematology

摘　　要：为了研究Bel亚型的血清学特征和遗传背景,采用红细胞凝集试验检测先证者及其家庭成员红细胞上的A、B、H抗原和血清中的抗A抗体、抗B抗体,用凝集抑制试验检测唾液中的A、B、H血型物质。结果表明:先证者与其母、女儿3人确定为Bel亚型;先证者的2个妹妹确定为ABel亚型;先证者的父亲、儿子和配偶分别为A、B和B型。结论:我国人群中Bel亚型是家族遗传。In order to study the serological characteristics and genetic background of Bel subtypes, A, B and H antigens on the surface of red blood cells of the proband as well as his family and the anti-A, anti-B antibodies in their serum samples were detected by hemagglufination test; the A, B, H substances in saliva were determined by inhibitory agglutination test. The results indicatad that the proband, his mother and his daughter all were identified to be Bel phenotype; his two sisters were identified to be ABel phenotype; his father, son and spouse were identified to be A, B and B phenotype respectively. It is concluded that the Bel subtype exists as family genetic characteristics in China.

关 键 词：ABO血型 弱B抗原 Bel亚型 家系调查 

分 类 号：R475.11[医药卫生—护理学]